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Application of a Non-invasive System for Monitoring Plasma Indocyanine Green Dynamics in Rats
http://hdl.handle.net/10191/33153
http://hdl.handle.net/10191/33153338b5675-e9bc-4b77-bbea-c9886a747e6b
名前 / ファイル | ライセンス | アクション |
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44(1)_19-22.pdf (468.1 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-08-27 | |||||
タイトル | ||||||
タイトル | Application of a Non-invasive System for Monitoring Plasma Indocyanine Green Dynamics in Rats | |||||
タイトル | ||||||
タイトル | Application of a Non-invasive System for Monitoring Plasma Indocyanine Green Dynamics in Rats | |||||
言語 | en | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatic dye test | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dye metabolism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Sakaguchi, Takeo
× Sakaguchi, Takeo× Fujita, Nobuhiro× Ishizuka, Dai× Aono, Takashi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A non-invasive indocyanine green (IGG) monitoring system was applied to rats to estimate the plasma disappearance rate of ICG (ICG-K). The optical sensor for monitoring the ICG concentration was attached to the skin of the forepaw of the posterior leg. When ICG 0.5 mg/kg (200μl) was injected into the jugular vein as a bolus, a plasma disappearance curve for ICG was obtained. The curve shifted downwards accoring to the decrease in the ICG dosage, and reproducible values in ICG-K were obtained when 0.25 mg/kg and 0.5 mg/kg ICG were injected. The curve obtained from the monitoring system was similar to that from the blood sampling method. It was also noted that the coefficients of variation in systemic arterial blood pressure and portal venous blood flow were both within 5 during the 15-min ICG examination. These results suggest that this ICG monitoring system is suitable for investigating the ICG metabolism with stable systemic and portal circulation in the rat. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 44, 号 1, p. 19-22, 発行日 1996-03 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
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収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
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値 | publisher |