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Isolation and Partial Characterization of Human Placenta Retinol-binding Protein
http://hdl.handle.net/10191/33138
http://hdl.handle.net/10191/331380aedf69b-31b6-4dbb-bfc5-d6584949278c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
45(4)_171-177.pdf (1.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-08-25 | |||||
| タイトル | ||||||
| タイトル | Isolation and Partial Characterization of Human Placenta Retinol-binding Protein | |||||
| タイトル | ||||||
| タイトル | Isolation and Partial Characterization of Human Placenta Retinol-binding Protein | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | retinol | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | retinol binding protein | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | placenta | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | vitamin A | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Kosaka, Hiroko
× Kosaka, Hiroko× Isemura, Mamoru× Odani, Shoji× Koide, Takehiko× Ono, Teruo |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Retinol-binding protein (RBP) is the specific blood carrier protein for the transport of retinol (vitamin A). RBP is mainly synthesized in the liver, though several extrahepatic organs including the placenta may also synthesize RBP as high amounts of RBP mRNA have been detected in these. Here we purified human placenta RBP (pRBP) and examined its characteristics in comparison with human plasma RBP (sRBP). pRBP showed cross-immunoreactivity with sRBP, but the difference was noted in the molecular weight as determined by SDS-PAGE. Since the amino-terminal amino acid sequence of pRBP was identical with that of sRBP, the lower molecular weight of pRBP suggests that pRBP is the truncated form in which several carboxyl-terminal amino acid residues of sRBP have been removed. pRBP can also be distinguished from sRBP in the elution pattern on high performance liquid chromatography and in the time course of fluorescence quenching of retinol bound as ligands to RBPs. These data suggest that pRBP may playa specific role in the placenta in connection with reports that extrahepatic RBP may be involved in the retinol transport and recycling. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 45, 号 4, p. 171-177, 発行日 1997-12 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Kosaka, Hiroko, Isemura, Mamoru, Odani, Shoji, Koide, Takehiko, Ono, Teruo, 1997, Isolation and Partial Characterization of Human Placenta Retinol-binding Protein: Niigata University School of Medicine, 171–177 p.
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