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The Effect of Pulsed Electromagnetic Fields on the Calcium Metabolism in Cultured Rabbit Chondrocytes
http://hdl.handle.net/10191/33073
http://hdl.handle.net/10191/330738a38d831-a2bb-463e-9553-cf5dd17b0791
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
46(1)_11-15.pdf (650.8 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-08-21 | |||||
| タイトル | ||||||
| タイトル | The Effect of Pulsed Electromagnetic Fields on the Calcium Metabolism in Cultured Rabbit Chondrocytes | |||||
| タイトル | ||||||
| タイトル | The Effect of Pulsed Electromagnetic Fields on the Calcium Metabolism in Cultured Rabbit Chondrocytes | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | pulsed electromagnetic fields | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | chondrocyte | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Verapamil | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | PTH | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Endo, Naoto
× Endo, Naoto× Takahashi, Hideaki E. |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We have previously demonstrated that pulsed electromagnetic fields (PEMF) affect the functional differentiation of rabbit growth plate chondrocytes in culture by enhancing the response of the parathyroid hormone (PTH). In this study, we examined whether the PEMF affect the proliferation of cultured chondrocytes as well as how their effect on the PTH response of the chondrocytes is related to the calcium metabolism. We cultured growth plate chondrocytes isolated from the ribs of young rabbits and treated them with Verapamil, a calcium blocker, under exposure to PEMF (pulsating recurrent burst, an average of 2 gauss). No significant effect on [3H] -thymidine incorporation into DNA synthesis in either the confluent or logarithmic phase was observed under exposure to PEMF. Verapamil: 1) inhibited DNA synthesis dose-dependently, whereas it did not change the level of glycosaminoglycan (GAG) synthesis; and 2) did not alter the level of PTH-dependent GAG synthesis in the presence or absence of PEMF. These findings indicated that PEMF stimuli resulted in the functional differentiation of growth plate chondrocytes by enhancing GAG synthesis in response to PTH, and that this effect was not affected by the change in the concentration of calcium ions. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 46, 号 1, p. 11-15, 発行日 1998-03 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
