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The Enterohemorrhagic Escherichia coli (EHEC) Hemolysin Genes of a Shiga Toxin (Stx1)- and Stx2-Producing, Serotype O128 Escherichia coliStrain with a Greatest Hemolytic Activity
http://hdl.handle.net/10191/1843
http://hdl.handle.net/10191/184345c7162d-9723-466c-a449-feaad617efad
名前 / ファイル | ライセンス | アクション |
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KJ00000007240.pdf (2.6 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2007-05-10 | |||||
タイトル | ||||||
タイトル | The Enterohemorrhagic Escherichia coli (EHEC) Hemolysin Genes of a Shiga Toxin (Stx1)- and Stx2-Producing, Serotype O128 Escherichia coliStrain with a Greatest Hemolytic Activity | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The Enterohemorrhagic Escherichia coli (EHEC) Hemolysin Genes of a Shiga Toxin (Stx1)- and Stx2-Producing, Serotype O128 Escherichia coliStrain with a Greatest Hemolytic Activity | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | enterohemorrhagic Escherichia coli (EHEC) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | serotype O128 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | EHEC-hemolysin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ABC-transporter | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
TANEIKE, Ikue
× TANEIKE, Ikue× WAKISAKA-SAITO, Noriko× HARADA, Yuki× ZHANG, Hui-Min× YAMAMOTO, Tatsuo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Most strains of enterohemorrhagic Escherichia coli (EHEC) belonging to serotypes O157,O26,O111,and O128,isolated from humans in Japan also produced EHEC-hemolysin (EHEC-hly), the hemolytic activity of whom was detected on blood agar containing washed but not unwashed sheep erythrocytes. Of those, Shiga toxin 1 (Stx1)- and Stx2-producing strains belonging to serotypes O128 : H2 and O128 : H12 produced EHEC-hly in much greater quantities than did the other strains. The two strains carried the EHEC-hly genes on the 120-kbp plasmid. The entire EHEC-hly region (carrying genes C, A, B, and D) of the serotype O128 : H12 strain was cloned into pACYC184 and sequenced. The EHEC O128-hly genes showed a close similarity to the the EHEC O157-hly genes of more than 98.3% at the nucleotide level (more than 97.7% at the amino acid level). However, the EHEC O128-hlyB (the ATP-binding transmembrane protein acting as a transporter for hemolysin [hlyA]) lacked one amino terminal methionine, in contrast to the repeated amino terminal methionines in the EHEC O157-hlyB. The O128- and O157-hly As shared similar RTX repeats and acylation sites. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 48, 号 1, p. 11-18, 発行日 2000-03 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |