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Lymph Node Metastasis and Micrometastasis of Submucosal Invasive Colorectal Carcinoma: An Indicator of the Curative Potential of Endoscopic Treatment
http://hdl.handle.net/10191/1917
http://hdl.handle.net/10191/1917022a6be5-4b7a-40ea-bd39-e304f0e4f02c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00000007306.pdf (2.0 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-05-10 | |||||
| タイトル | ||||||
| タイトル | Lymph Node Metastasis and Micrometastasis of Submucosal Invasive Colorectal Carcinoma: An Indicator of the Curative Potential of Endoscopic Treatment | |||||
| タイトル | ||||||
| タイトル | Lymph Node Metastasis and Micrometastasis of Submucosal Invasive Colorectal Carcinoma: An Indicator of the Curative Potential of Endoscopic Treatment | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | lymph node metastasis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | micrometastasis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | submucosal colorectal carcinoma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | endoscopic treatment | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Yokoyama, Junji
× Yokoyama, Junji× Ajioka, Yoichi× Watanabe, Hidenobu× Asakura, Hitoshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study investigated the correlation between clinicopathologic features of submucosal invasive colorectal carcinoma (sm-CRC) and its metastasis to the lymph nodes, including micrometastasis dectected by anti-human cytokeratin (CAM5.2) immunohistochemistry, in order to assess the curative potential of endoscopic mucosal resection (EMR) for sm-CRC. One hundred seventeen surgically resected sm-CRCs and their corresponding regional lymph nodes were examined. Eighteen of the 117 cases (15.4%) were positive for lymph node metastasis by H&E examination (overt metastasis), and micrometastasis was detected in 17 of the 99 (17.2%) remaining cases that were negative for overt metastasis. Lymphatic invasion and sprouting were risk factors for overt/micrometastasis, and micrometastasis, respectively, (p<0.0001/p=0.03,and p=0.01), and the minimum extent of cancer invasion in patients with lymph node metastasis (micrometastasis) was 850 μm in depth and 2500 μm in width. Tumors with a smaller extent of submucosal invasion than these values showed no lymphatic or venous invasion or sprouting. The present study indicates that sm-CRCs with an extent of submucosal invasion of less than 850 μm in depth and 2500 μm in width may not even have any risk of micrometastasis, and that EMR alone has complete curative potential in such cases. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 50, 号 1, p. 1-8, 発行日 2002-03 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
