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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.51 No.2

The Relationship of Serum Levels of Malondialdehyde-modified Low Density Lipoprotein to Serum Lipids and Anthropometric Measurements in School Children

http://hdl.handle.net/10191/1886
http://hdl.handle.net/10191/1886
804cb46d-b591-40c4-b3d6-dbec9d77bd88
名前 / ファイル ライセンス アクション
KJ00000007367.pdf KJ00000007367.pdf (3.8 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-05-10
タイトル
タイトル The Relationship of Serum Levels of Malondialdehyde-modified Low Density Lipoprotein to Serum Lipids and Anthropometric Measurements in School Children
タイトル
言語 en
タイトル The Relationship of Serum Levels of Malondialdehyde-modified Low Density Lipoprotein to Serum Lipids and Anthropometric Measurements in School Children
言語
言語 eng
キーワード
主題Scheme Other
主題 malondialdehyde-modified LDL
キーワード
主題Scheme Other
主題 child
キーワード
主題Scheme Other
主題 obesity
キーワード
主題Scheme Other
主題 primary prevention
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 KAMEDA, Kazuhiro

× KAMEDA, Kazuhiro

WEKO 52040

KAMEDA, Kazuhiro

Search repository
KIKUCHI, Toru

× KIKUCHI, Toru

WEKO 52041

KIKUCHI, Toru

Search repository
YAMAZAKI, Hisashi

× YAMAZAKI, Hisashi

WEKO 52042

YAMAZAKI, Hisashi

Search repository
HIURA, Makoto

× HIURA, Makoto

WEKO 52043

HIURA, Makoto

Search repository
UCHIYAMA, Makoto

× UCHIYAMA, Makoto

WEKO 52044

UCHIYAMA, Makoto

Search repository
抄録
内容記述タイプ Abstract
内容記述 The aim of this study was to reveal the serum levels of malondialdehyde-modified LDL (MDA-LDL), which is one of the oxidative LDL, and the relationships of serum MDA-LDL to serum lipids and apolipoproteins, and obesity in children. Japanese school boys (36 obese and 101 nonobese) and girls (24 obese 111 nonobese) aged from 10 to 14 years were examined. Serum MDA-LDL levels were measured by the double-antibody sandwich ELISA method. Serum LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), triglycerid (TC), apolipoprotein A1 (Apo A1), apolipoprotein B (Apo B), and apolipoprotein E (Apo E) levels were measured using an automatic analyzer. Height and weight were measured, and percent of relative weight, body mass index (BMI), were calculated. The serum MDA-LDL levels were 58.9±6.8 U/1 (obese, 68.3±24.1 IU/l; nonobese, 55.6±16.2) in boys and 56.3±19.5 U/l (obese, 62.9±27.5 IU/l; nonobese, 54.9±17.1) in girls. The serum MDA-LDL levels in obese boys were significantly higher than those in nonobese boys (p<0.001). The serum MDA-LDL levels in obese girls had a tendency to be higher than those in nonobese girls (p=0.06). In both sexes, the serum MDA-LDL levels showed a significantly positive correlation with serum LDL-C, TC, Apo B and Apo E levels and percent of relative weight, BMI, and showed a significantly inverse correlation with the serum HDL-C levels. Children with dyslipidemia and/or obesity might already have higher MDA-LDL levels and atherosclerotic lesions. They therefore should be monitored for the prevention of atherosclerotic disease from childhood.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 51, 号 2, p. 67-73, 発行日 2003-06
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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