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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.51 No.2

The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test

http://hdl.handle.net/10191/1887
http://hdl.handle.net/10191/1887
23fbbb84-6777-41e2-96d9-5fbdbf30b405
名前 / ファイル ライセンス アクション
KJ00000007364.pdf KJ00000007364.pdf (4.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-05-10
タイトル
タイトル The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test
タイトル
言語 en
タイトル The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test
言語
言語 eng
キーワード
主題Scheme Other
主題 metoprolol
キーワード
主題Scheme Other
主題 carvedilol
キーワード
主題Scheme Other
主題 mental stress
キーワード
主題Scheme Other
主題 color word conflict test
キーワード
主題Scheme Other
主題 β-blocker
キーワード
主題Scheme Other
主題 heart rate
キーワード
主題Scheme Other
主題 blood pressure
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 WATANABE, Yasuo

× WATANABE, Yasuo

WEKO 52027

WATANABE, Yasuo

Search repository
OKADA, Masayoshi

× OKADA, Masayoshi

WEKO 52028

OKADA, Masayoshi

Search repository
TSURUMAKI, Tatsuru

× TSURUMAKI, Tatsuru

WEKO 52029

TSURUMAKI, Tatsuru

Search repository
GEJYO, Fumitake

× GEJYO, Fumitake

WEKO 52030

GEJYO, Fumitake

Search repository
HIGUCHI, Hiroshi

× HIGUCHI, Hiroshi

WEKO 52031

HIGUCHI, Hiroshi

Search repository
抄録
内容記述タイプ Abstract
内容記述 Experimental mental stress by a computerized color word conflict test was developed. The effects of a single oral administration of two different β-blockers, carvedilol (a vasodilating β-/α_1-blocker, 20 mg) and metoprolol (a β_1-selective blocker, 20 mg), on a color word conflict test (mental stress)-induced increase in heart rate and systolic blood pressure were investigated in 108 healthy volunteers, 21-24 years of age, by double blind protocol. At rest carvedilol and metoprolol gradually reduced the heart rate, and slightly lowered systolic and diastolic blood pressure. The mental stress by the color word conflict test significantly increased the heart rate and systolic blood pressure by a respective 3.1±0.6/min and 2.0±0.9mmHg. Carvedilol completely inhibited the mental stress-induced increases in both systolic blood pressure and heart rate 3 h after administration, and metoprolol significantly blocked the increase in systolic blood pressure. These findings indicated that β-blockers effectively prevent mental stress-induced changes in cardiovascular functions.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 51, 号 2, p. 43-48, 発行日 2003-06
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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