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The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test
http://hdl.handle.net/10191/1887
http://hdl.handle.net/10191/188723fbbb84-6777-41e2-96d9-5fbdbf30b405
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00000007364.pdf (4.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-05-10 | |||||
| タイトル | ||||||
| タイトル | The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test | |||||
| タイトル | ||||||
| タイトル | The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | metoprolol | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | carvedilol | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | mental stress | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | color word conflict test | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | β-blocker | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | heart rate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | blood pressure | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
WATANABE, Yasuo
× WATANABE, Yasuo× OKADA, Masayoshi× TSURUMAKI, Tatsuru× GEJYO, Fumitake× HIGUCHI, Hiroshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Experimental mental stress by a computerized color word conflict test was developed. The effects of a single oral administration of two different β-blockers, carvedilol (a vasodilating β-/α_1-blocker, 20 mg) and metoprolol (a β_1-selective blocker, 20 mg), on a color word conflict test (mental stress)-induced increase in heart rate and systolic blood pressure were investigated in 108 healthy volunteers, 21-24 years of age, by double blind protocol. At rest carvedilol and metoprolol gradually reduced the heart rate, and slightly lowered systolic and diastolic blood pressure. The mental stress by the color word conflict test significantly increased the heart rate and systolic blood pressure by a respective 3.1±0.6/min and 2.0±0.9mmHg. Carvedilol completely inhibited the mental stress-induced increases in both systolic blood pressure and heart rate 3 h after administration, and metoprolol significantly blocked the increase in systolic blood pressure. These findings indicated that β-blockers effectively prevent mental stress-induced changes in cardiovascular functions. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 51, 号 2, p. 43-48, 発行日 2003-06 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
