{"_buckets": {"deposit": "bbb72033-b615-496e-ad03-c8679075181f"}, "_deposit": {"id": "6267", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6267"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006267", "sets": ["456", "592"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2003-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "48", "bibliographicPageStart": "43", "bibliographicVolumeNumber": "51", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Experimental mental stress by a computerized color word conflict test was developed. The effects of a single oral administration of two different β-blockers, carvedilol (a vasodilating β-/α_1-blocker, 20 mg) and metoprolol (a β_1-selective blocker, 20 mg), on a color word conflict test (mental stress)-induced increase in heart rate and systolic blood pressure were investigated in 108 healthy volunteers, 21-24 years of age, by double blind protocol. At rest carvedilol and metoprolol gradually reduced the heart rate, and slightly lowered systolic and diastolic blood pressure. The mental stress by the color word conflict test significantly increased the heart rate and systolic blood pressure by a respective 3.1±0.6/min and 2.0±0.9mmHg. Carvedilol completely inhibited the mental stress-induced increases in both systolic blood pressure and heart rate 3 h after administration, and metoprolol significantly blocked the increase in systolic blood pressure. These findings indicated that β-blockers effectively prevent mental stress-induced changes in cardiovascular functions.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "WATANABE, Yasuo"}], "nameIdentifiers": [{"nameIdentifier": "52027", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "OKADA, Masayoshi"}], "nameIdentifiers": [{"nameIdentifier": "52028", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TSURUMAKI, Tatsuru"}], "nameIdentifiers": [{"nameIdentifier": "52029", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "GEJYO, Fumitake"}], "nameIdentifiers": [{"nameIdentifier": "52030", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HIGUCHI, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "52031", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000007364.pdf", "filesize": [{"value": "4.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 4200000.0, "url": {"label": "KJ00000007364.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6267/files/KJ00000007364.pdf"}, "version_id": "22aaac2f-bcb8-4597-854a-2b52c27c50e6"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "metoprolol", "subitem_subject_scheme": "Other"}, {"subitem_subject": "carvedilol", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mental stress", "subitem_subject_scheme": "Other"}, {"subitem_subject": "color word conflict test", "subitem_subject_scheme": "Other"}, {"subitem_subject": "β-blocker", "subitem_subject_scheme": "Other"}, {"subitem_subject": "heart rate", "subitem_subject_scheme": "Other"}, {"subitem_subject": "blood pressure", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test"}, {"subitem_title": "The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "592"], "permalink_uri": "http://hdl.handle.net/10191/1887", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-05-10"}, "publish_date": "2007-05-10", "publish_status": "0", "recid": "6267", "relation": {}, "relation_version_is_last": true, "title": ["The Preventive Effect of β-blockers, Carvedilol and Metoprolol, on Mental Stress-induced Changes in Cardiovascular Functions by a Color Word Conflict Test"], "weko_shared_id": null}