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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.52 No.2

Definition and Histogenesis of Ovarian-type Stroma in Mucinous Cystic Neoplasms of the Pancreas

http://hdl.handle.net/10191/1826
http://hdl.handle.net/10191/1826
5113d724-045e-4f5e-b5df-117af20c2f19
名前 / ファイル ライセンス アクション
KJ00004271969.pdf KJ00004271969.pdf (7.1 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-05-10
タイトル
タイトル Definition and Histogenesis of Ovarian-type Stroma in Mucinous Cystic Neoplasms of the Pancreas
タイトル
言語 en
タイトル Definition and Histogenesis of Ovarian-type Stroma in Mucinous Cystic Neoplasms of the Pancreas
言語
言語 eng
キーワード
主題Scheme Other
主題 pancreatic tumor
キーワード
主題Scheme Other
主題 mucinous cystic neoplasm
キーワード
主題Scheme Other
主題 intraductal papillary mucinous neoplasm
キーワード
主題Scheme Other
主題 ovarian-type stroma
キーワード
主題Scheme Other
主題 estrogen receptor
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Kurosaki, Ryo

× Kurosaki, Ryo

WEKO 51910

Kurosaki, Ryo

Search repository
Ajioka, Yoichi

× Ajioka, Yoichi

WEKO 51911

Ajioka, Yoichi

Search repository
Shirai, Yoshio

× Shirai, Yoshio

WEKO 51912

Shirai, Yoshio

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Watanabe, Hidenobu

× Watanabe, Hidenobu

WEKO 51913

Watanabe, Hidenobu

Search repository
Emura, Iwao

× Emura, Iwao

WEKO 51914

Emura, Iwao

Search repository
Ohta, Tamaki

× Ohta, Tamaki

WEKO 51915

Ohta, Tamaki

Search repository
Tsuchiya, Yoshiaki

× Tsuchiya, Yoshiaki

WEKO 51916

Tsuchiya, Yoshiaki

Search repository
Yamano, Miki

× Yamano, Miki

WEKO 51917

Yamano, Miki

Search repository
Hatakeyama, Katsuyoshi

× Hatakeyama, Katsuyoshi

WEKO 51918

Hatakeyama, Katsuyoshi

Search repository
抄録
内容記述タイプ Abstract
内容記述 Objectives: The present study aimed to clarify the definitions and histogenesis of ovarian-type stroma (OTS) in mucinous cystic neoplasms (MCNs) of the pancreas. Methods: Expression and density of cells positive for estrogen receptor (ER) and progesterone receptor (PR) were immunohistochemically studied in 16 MCNs (6 adenomas, 10 carcinomas), 22 intraductal papillary mucinous neoplasms (IPMNs), 10 common-type invasive ductal carcinomas (IDCs) and 24 non-neoplastic pancreatic tissues. Results: OTS comprised densely packed spindleshaped cells with round or elongated nuclei. Stromal cells were diffusely positive for ER and PR in all 16 MCNs. OTS-like stromal cells in IPMNs and IDCs were negative or only sporadically positive for ER or PR in all cases. In non-neoplastic pancreatic tissue, ER- and PR-reactive stromal cells were scattered sporadically irrespective of site in the pancreas (head, body or tail) or sex. Conclusions: OTS is an absolute marker for diagnosis of pancreatic MCNs and should be confirmed as ER- and PR-reactive on immunostaining in addition to findings from sections stained using hematoxylin-eosin. ER- and PR-reactive stromal cells may become hypersensitive to female sex hormone stimulation and start to proliferate and form OTS in the pancreas.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 52, 号 2, p. 57-65, 発行日 2004-06
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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