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Glia-derived Inhibitors of Axonal Regrowth : Implication for the Molecular Strategy of Axonal Regeneration
http://hdl.handle.net/10191/1928
http://hdl.handle.net/10191/19284d575085-875f-4c53-9f11-3722c8760f9e
名前 / ファイル | ライセンス | アクション |
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KJ00004355698.pdf (2.5 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2007-05-10 | |||||
タイトル | ||||||
タイトル | Glia-derived Inhibitors of Axonal Regrowth : Implication for the Molecular Strategy of Axonal Regeneration | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Glia-derived Inhibitors of Axonal Regrowth : Implication for the Molecular Strategy of Axonal Regeneration | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | growth cone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chondroitin sulfate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | nogo | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | myelin-associated glycoprotein (MAG) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | nogo receptor (NgR). | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
IGARASHI, Michihiro
× IGARASHI, Michihiro× SATO, Michiyuki |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Axonal injury causes fatal damage to the neuron because of the poor regrowth of the injured axon. This phenomenon is one of the most critical reasons why neurological diseases are currently intractable. Recent studies have revealed that a part of the poor axonal regeneration is caused by the presence of the inhibitors to axonal regrowth, derived from glial cells surrounding the axon. Known molecules such as chondroitin sulfate proteoglycan and myelin-associated glycoprotein (MAG), derived from the astrocyte and the oligodendrocyte, respectively, are thought to be involved in the inhibition of the axonal regeneration. Here, we summarize the current findings on regarding the actions of these molecules, and survey strategies for treating the axonal injury from clinical aspects. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 53, 号 3, p. 65-72, 発行日 2005-09 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |