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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.56 No.1

Regular Exercise Improves Insulin Sensitivity, Physical Activity, and Psychosocial Status in Patients with Chronic Liver Diseases

http://hdl.handle.net/10191/19590
http://hdl.handle.net/10191/19590
71cd95cf-d092-4d7c-99a7-9822cb49118d
名前 / ファイル ライセンス アクション
110007138518.pdf 110007138518.pdf (908.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-09-28
タイトル
タイトル Regular Exercise Improves Insulin Sensitivity, Physical Activity, and Psychosocial Status in Patients with Chronic Liver Diseases
タイトル
言語 en
タイトル Regular Exercise Improves Insulin Sensitivity, Physical Activity, and Psychosocial Status in Patients with Chronic Liver Diseases
言語
言語 eng
キーワード
主題Scheme Other
主題 liver diseases
キーワード
主題Scheme Other
主題 exercise
キーワード
主題Scheme Other
主題 insulin resistance
キーワード
主題Scheme Other
主題 quality of life
キーワード
主題Scheme Other
主題 branched-chain amino acids
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Kobayashi, Makoto

× Kobayashi, Makoto

WEKO 51527

Kobayashi, Makoto

Search repository
Suda, Takeshi

× Suda, Takeshi

WEKO 51528

Suda, Takeshi

Search repository
Hashiba, Masao

× Hashiba, Masao

WEKO 51529

Hashiba, Masao

Search repository
Nagasaki, Koji

× Nagasaki, Koji

WEKO 51530

Nagasaki, Koji

Search repository
Adachi, Aiko

× Adachi, Aiko

WEKO 51531

Adachi, Aiko

Search repository
Nomoto, Minoru

× Nomoto, Minoru

WEKO 51532

Nomoto, Minoru

Search repository
Arakawa, Masaaki

× Arakawa, Masaaki

WEKO 51533

Arakawa, Masaaki

Search repository
Aoyagi, Yutaka

× Aoyagi, Yutaka

WEKO 51534

Aoyagi, Yutaka

Search repository
抄録
内容記述タイプ Abstract
内容記述 Limitations to physical activity lead to impairments of insulin sensitivity and deterioration of health related quality of life (HRQOL) in patients with chronic liver diseases (CLD). The effects of regular exercise on physical and psychosocial factors were prospectively evaluated in CLD. Five patients with various etiologies and stages were enrolled. Daily aerobic and resistance trainings were conducted for a course of five months with an oral intake of branched-chain amino acids (BCAA) starting one month prior to the exercise. Various biochemical, physical parameters, and profile of mood states (POMS) were measured before and after the course. Statistical significance was evaluated using a resampling method. No event was marked during the course to require additional treatments. A significant improvement in insulin sensitivity was observed as reductions of fasting blood glucose and serum insulin levels. Physical capability was significantly improved in both strength and endurance as increments of grasping and knee extension powers, and ventilatory threshold. The fatigue score was significantly reduced in accordance with a decreasing tendency of all other negative aspects in POMS. While significant decreases in serum concentrations of cholinesterase and prealbumin, platelet count, and bone mass were observed, serum concentrations of transferrin and BCAA as well as prothrombin activity showed increasing tendency. Regular exercise could be a promising alternative to improve insulin sensitivity and HRQOL in CLD, though medications and close evaluation should be conducted for possibilities of osteoporosis and hemorrhagic events.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 56, 号 1, p. 1-9, 発行日 2008-03
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
権利
権利情報 本文データは学協会の許諾に基づきCiNiiから複製したものである
著者版フラグ
値 publisher
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