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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

Factors Affecting the Baseline and Post-Treatment Scores on the Hopkins Verbal Learning Test-Revised Japanese Version before and after Whole-Brain Radiation Therapy

http://hdl.handle.net/10191/50441
http://hdl.handle.net/10191/50441
056bd790-a6a7-489d-967f-5d77103c21e0
名前 / ファイル ライセンス アクション
h29nmk797.pdf 本文 (970.7 kB)
h29nmk797_a.pdf 要旨 (675.1 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2018-07-26
タイトル
タイトル Factors Affecting the Baseline and Post-Treatment Scores on the Hopkins Verbal Learning Test-Revised Japanese Version before and after Whole-Brain Radiation Therapy
タイトル
言語 en
タイトル Factors Affecting the Baseline and Post-Treatment Scores on the Hopkins Verbal Learning Test-Revised Japanese Version before and after Whole-Brain Radiation Therapy
言語
言語 eng
キーワード
主題Scheme Other
主題 brain metastasis
キーワード
主題Scheme Other
主題 whole-brain radiation therapy
キーワード
主題Scheme Other
主題 Hopkins Verbal Learning Test-Revised
キーワード
主題Scheme Other
主題 neurocognitive function
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル 全脳照射前後での日本語版ホプキンス言語学習試験の点数に影響する因子
著者 Saito, Hirotake

× Saito, Hirotake

WEKO 51218

Saito, Hirotake

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著者別名
識別子 51219
識別子Scheme WEKO
姓名 斎藤, 紘丈
抄録
内容記述タイプ Abstract
内容記述 Our objectives were to (1) investigate the feasibility of the use of the Japanese version of the Hopkins Verbal Learning Test-Revised (HVLT-R); (2) identify the clinical factors influencing the HVLT-R scores of patients undergoing whole-brain radiation therapy (WBRT); and (3) compare the neurocognitive function (NCF) after WBRT in different dose fractionation schedules. We administered the HVLT-R (Japanese version) before (baseline) and at four and eight months after WBRT in 45 patients who received either therapeutic (35Gy-in-14, n = 16; 30Gy-in-10, n = 18) or prophylactic (25Gy-in-10, n = 11) WBRT. Sixteen patients dropped out before the eight-month examination, due mostly to death from cancer. The Karnofsky Performance Status (KPS) 80–100 group had significantly higher baseline total recall (TR) scores (p = 0.0053), delayed recall (DR) scores (p = 0.012), and delayed recognition (DRecog) scores (p = 0.0078). The patients aged _65 years also had significantly higher TR scores (p = 0.030) and DRecog scores (p = 0.031). The patients who underwent two examinations (worse-prognosis group) had significantly decreased DR scores four months after WBRT compared to the baseline (p = 0.0073), and they were significantly more likely to have declined individual TR scores (p = 0.0017) and DR scores (p = 0.035) at four months. The eight-month HVLT-R scores did not significantly decline regardless of the WBRT dose fractionation. The baseline NCF was determined by age and KPS, and the early decline in NCF is characteristic of the worse-prognosis group.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(医学). 報告番号: 甲第4398号. 学位記番号: 新大院博(医)甲第797号. 学位授与年月日: 平成30年3月23日
内容記述
内容記述タイプ Other
内容記述 International Journal of Molecular Sciences. 2016. 17(11), 1834.
書誌情報 p. 1-12, 発行日 2018-03-23
出版者
出版者 新潟大学
DOI
識別子タイプ DOI
関連識別子 info:doi/10.3390/ijms17111834
権利
権利情報 (c) 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
著者版フラグ
値 ETD
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2018-03-23
学位授与番号
学位授与番号 13101甲第4398号
学位記番号
内容記述タイプ Other
内容記述 新大院博(医)甲第797号
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