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Nomogram for 5-year relapse-free survival of a patient with advanced gastric cancer after surgery
http://hdl.handle.net/10191/50434
http://hdl.handle.net/10191/504344efa5a2c-f8bd-4ca5-bebc-e4b0b8946577
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2018-07-26 | |||||
タイトル | ||||||
タイトル | Nomogram for 5-year relapse-free survival of a patient with advanced gastric cancer after surgery | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Nomogram for 5-year relapse-free survival of a patient with advanced gastric cancer after surgery | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nomogram | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Prediction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Advanced gastric cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Recurrence risk | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cox proportional hazards regression model | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | 進行胃癌に対する根治切除術後の再発予後予測ノモグラムの検討 | |||||
著者 |
Muneoka, Yusuke
× Muneoka, Yusuke |
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著者別名 | ||||||
識別子 | 51215 | |||||
識別子Scheme | WEKO | |||||
姓名 | 宗岡, 悠介 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Prognoses vary substantially among patients with advanced gastric cancer following curative surgery. The aim of the current study was to develop and verify the validity of a novel nomogram that predicts the probability of 5-year relapse-free survival (RFS) in patients who underwent curative resection for stage II/III gastric cancer. Materials and methods: A nomogram to predict 5-year RFS following surgical resection of gastric cancer was constructed based on the data of patients who underwent surgery for primary gastric carcinoma at three institutions in Japan in January 2001-December 2006. Multivariate analysis using a Cox proportional hazards regression model was performed, and the nomogram's predictive accuracy (discrimination) and the agreement between observed outcomes and predictions (calibration) were evaluated by internal validation. Results: Multivariate analyses revealed that age at operation, depth of tumor, tumor location, lymph node classification, and presence of combined resection were significant prognostic factors for RFS. In the internal validation, discrimination of the developed nomogram for 5-year RFS was superior to that of the American Joint Committee on Cancer TNM classification (concordance indices of 0.80 versus 0.67; P < 0.001). Moreover, calibration appeared to be accurate. Based on these results, we have created free software to more easily predict 5-year RFS. Conclusion: We developed and validated a nomogram to predict 5-year RFS after curative surgery for stage II/III gastric cancer. This tool will be useful for the assessing a patient's individual recurrence risk when considering additional therapy in clinical practice. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 学位の種類: 博士(医学). 報告番号: 甲第4396号. 学位記番号: 新大院博(医)甲第795号. 学位授与年月日: 平成30年3月23日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | International Journal of Surgery. 2016. 35, 153-159. | |||||
書誌情報 | p. 153-159, 発行日 2018-03-23 | |||||
出版者 | ||||||
出版者 | 新潟大学 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1016/j.ijsu.2016.09.080 | |||||
権利 | ||||||
権利情報 | Elsevier | |||||
著者版フラグ | ||||||
値 | ETD | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 新潟大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2018-03-23 | |||||
学位授与番号 | ||||||
学位授与番号 | 13101甲第4396号 | |||||
学位記番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新大院博(医)甲第795号 |