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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

Nomogram for 5-year relapse-free survival of a patient with advanced gastric cancer after surgery

http://hdl.handle.net/10191/50434
http://hdl.handle.net/10191/50434
4efa5a2c-f8bd-4ca5-bebc-e4b0b8946577
名前 / ファイル ライセンス アクション
h29nmk795.pdf 本文 (604.5 kB)
h29nmk795_a.pdf 要旨 (587.1 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2018-07-26
タイトル
タイトル Nomogram for 5-year relapse-free survival of a patient with advanced gastric cancer after surgery
タイトル
言語 en
タイトル Nomogram for 5-year relapse-free survival of a patient with advanced gastric cancer after surgery
言語
言語 eng
キーワード
主題Scheme Other
主題 Nomogram
キーワード
主題Scheme Other
主題 Prediction
キーワード
主題Scheme Other
主題 Advanced gastric cancer
キーワード
主題Scheme Other
主題 Recurrence risk
キーワード
主題Scheme Other
主題 Cox proportional hazards regression model
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル 進行胃癌に対する根治切除術後の再発予後予測ノモグラムの検討
著者 Muneoka, Yusuke

× Muneoka, Yusuke

WEKO 51214

Muneoka, Yusuke

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著者別名
識別子 51215
識別子Scheme WEKO
姓名 宗岡, 悠介
抄録
内容記述タイプ Abstract
内容記述 Background: Prognoses vary substantially among patients with advanced gastric cancer following curative surgery. The aim of the current study was to develop and verify the validity of a novel nomogram that predicts the probability of 5-year relapse-free survival (RFS) in patients who underwent curative resection for stage II/III gastric cancer. Materials and methods: A nomogram to predict 5-year RFS following surgical resection of gastric cancer was constructed based on the data of patients who underwent surgery for primary gastric carcinoma at three institutions in Japan in January 2001-December 2006. Multivariate analysis using a Cox proportional hazards regression model was performed, and the nomogram's predictive accuracy (discrimination) and the agreement between observed outcomes and predictions (calibration) were evaluated by internal validation. Results: Multivariate analyses revealed that age at operation, depth of tumor, tumor location, lymph node classification, and presence of combined resection were significant prognostic factors for RFS. In the internal validation, discrimination of the developed nomogram for 5-year RFS was superior to that of the American Joint Committee on Cancer TNM classification (concordance indices of 0.80 versus 0.67; P < 0.001). Moreover, calibration appeared to be accurate. Based on these results, we have created free software to more easily predict 5-year RFS. Conclusion: We developed and validated a nomogram to predict 5-year RFS after curative surgery for stage II/III gastric cancer. This tool will be useful for the assessing a patient's individual recurrence risk when considering additional therapy in clinical practice.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(医学). 報告番号: 甲第4396号. 学位記番号: 新大院博(医)甲第795号. 学位授与年月日: 平成30年3月23日
内容記述
内容記述タイプ Other
内容記述 International Journal of Surgery. 2016. 35, 153-159.
書誌情報 p. 153-159, 発行日 2018-03-23
出版者
出版者 新潟大学
DOI
識別子タイプ DOI
関連識別子 info:doi/10.1016/j.ijsu.2016.09.080
権利
権利情報 Elsevier
著者版フラグ
値 ETD
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2018-03-23
学位授与番号
学位授与番号 13101甲第4396号
学位記番号
内容記述タイプ Other
内容記述 新大院博(医)甲第795号
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