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Effect of a neural relay on liver regeneration in mice : activation of serotonin release from the gastrointestinal tract
http://hdl.handle.net/10191/50422
http://hdl.handle.net/10191/504220aed74c9-5d31-4373-9c23-240b939c5fef
名前 / ファイル | ライセンス | アクション |
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要旨 (595.0 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2018-07-26 | |||||
タイトル | ||||||
タイトル | Effect of a neural relay on liver regeneration in mice : activation of serotonin release from the gastrointestinal tract | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effect of a neural relay on liver regeneration in mice : activation of serotonin release from the gastrointestinal tract | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | neural relay | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver regeneration | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gastrointestinal tract | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hormone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | serotonin | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | 肝障害時の神経ネットワークを介した、消化管からのセロトニン分泌による肝再生への寄与の検証 | |||||
著者 |
Inoue, Ryosuke
× Inoue, Ryosuke |
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著者別名 | ||||||
識別子 | 51197 | |||||
識別子Scheme | WEKO | |||||
姓名 | 井上, 良介 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The development of therapeutic options to promote hepatic regeneration following severe liver injury is essential. While humoral factors have been reported as mechanisms of liver regeneration, the contributions of inter-organ communication to liver regeneration have not been reported. In this study, we examined the effect of a neural relay on liver regeneration via activation of serotonin release from the gastrointestinal tract. Our results demonstrated that the afferent visceral nerve from the liver activates the efferent vagus nerve from the brain, leading to activation of serotonin release from the gastrointestinal tract and contributing to liver regeneration. While it is difficult to apply these results directly to human health, we believe that this study may represent a step forwards developing essential therapeutics to promote liver regeneration. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 学位の種類: 博士(医学). 報告番号: 甲第4387号. 学位記番号: 新大院博(医)甲第786号. 学位授与年月日: 平成30年3月23日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | FEBS Open Bio. 2018. 8(3), 449-460. | |||||
書誌情報 | p. 1-33, 発行日 2018-03-23 | |||||
出版者 | ||||||
出版者 | 新潟大学 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1002/2211-5463.12382 | |||||
権利 | ||||||
権利情報 | (C) 2018 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
値 | ETD | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 新潟大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2018-03-23 | |||||
学位授与番号 | ||||||
学位授与番号 | 13101甲第4387号 | |||||
学位記番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新大院博(医)甲第786号 |