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Association between all-cause mortality and severity of depressive symptoms in patients with type 2 diabetes : analysis from the Japan Diabetes Complications Study (JDCS)
http://hdl.handle.net/10191/48150
http://hdl.handle.net/10191/4815034670475-42b8-41d1-8b20-eda9db36e783
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本文 (277.2 kB)
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要旨 (156.7 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2017-11-07 | |||||
| タイトル | ||||||
| タイトル | Association between all-cause mortality and severity of depressive symptoms in patients with type 2 diabetes : analysis from the Japan Diabetes Complications Study (JDCS) | |||||
| タイトル | ||||||
| タイトル | Association between all-cause mortality and severity of depressive symptoms in patients with type 2 diabetes : analysis from the Japan Diabetes Complications Study (JDCS) | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Diabetes mellitus, type 2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Depressive disorder | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Death | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypoglycemia | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_46ec | |||||
| タイプ | thesis | |||||
| その他のタイトル | ||||||
| その他のタイトル | 2型糖尿病患者におけるうつ症状重症度と全死因死亡の関係に関する検討 | |||||
| 著者 |
Matsunaga, Satoshi
× Matsunaga, Satoshi |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 51148 | |||||
| 姓名 | 松永, 佐澄志 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objective: The aims of this study are to confirm whether the excess mortality caused by depressive symptoms is independent of severe hypoglycemia in patients with type 2 diabetes mellitus (T2DM) and to evaluate the association between all-cause mortality and degrees of severity of depressive symptoms in Japanese patients with T2DM. Methods: A total of 1160 Japanese patients with T2DM were eligible for this analysis. Participants were followed prospectively for 3 years and their depressive states were evaluated at baseline by the Center for Epidemiologic Studies Depression Scale (CES-D). Cox proportional hazards model was used to evaluate the relative risk of allcause mortality and was adjusted by possible confounding factors, including severe hypoglycemia, all of which are known as risk factors for both depression and mortality. Results: After adjustment for severe hypoglycemia, each 5-point increase in the CES-D score was significantly associated with excess all-cause mortality (hazard ratio 1.69 [95% CI 1.26.2.17]). The spline curve of HRs for mortality according to total CES-D scores showed that mortality risk was slightly increased at lower scores but was sharply elevated at higher scores. Conclusion: A high score on the CES-D at baseline was significantly associated with all-cause mortality in patients with T2DM after adjusting for confounders including severe hypoglycemia. However, only a small effect on mortality risk was found at relatively lower levels of depressive symptoms in this population. Further research is needed to confirm this relationship between the severity of depressive symptoms and mortality in patients with T2DM. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 学位の種類: 博士（医学）. 報告番号: 甲第4361号. 学位記番号: 新大院博（医）甲第774号. 学位授与年月日: 平成29年9月20日 | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Journal of Psychosomatic Research. 2017, 99, 34–39. | |||||
| 書誌情報 | 発行日 2017-09-20 | |||||
| 出版者 | ||||||
| 出版者 | 新潟大学 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1016/j.jpsychores.2017.05.020 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2017 Elsevier Inc. All rights reserved. | |||||
| 著者版フラグ | ||||||
| 値 | ETD | |||||
| 学位名 | ||||||
| 学位名 | 博士（医学） | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 新潟大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2017-09-20 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 13101甲第4361号 | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 新大院博（医）甲第774号 | |||||
