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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

Cortico-cortical evoked hemodynamic responses in human language systems using intraoperative near-infrared spectroscopy during direct cortical stimulation.

http://hdl.handle.net/10191/47584
52c37e91-fffe-41c9-9d67-3385f17fef11
名前 / ファイル ライセンス アクション
h28nmk731.pdf 本文 (894.1 kB)
h28nmk731_a.pdf 要旨 (211.7 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2018-09-11
タイトル
タイトル Cortico-cortical evoked hemodynamic responses in human language systems using intraoperative near-infrared spectroscopy during direct cortical stimulation.
タイトル
言語 en
タイトル Cortico-cortical evoked hemodynamic responses in human language systems using intraoperative near-infrared spectroscopy during direct cortical stimulation.
言語
言語 eng
キーワード
主題Scheme Other
主題 Cortico-cortical network
キーワード
主題Scheme Other
主題 Direct cortical stimulation
キーワード
主題Scheme Other
主題 Epilepsy surgery
キーワード
主題Scheme Other
主題 Language systems
キーワード
主題Scheme Other
主題 Near-infrared spectroscopy
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル 術中皮質電気刺激下NIRS同時記録による, ヒト言語野(前頭葉-側頭葉)における皮質-皮質間誘発血流変化の検討
著者 Sato, Keisuke

× Sato, Keisuke

WEKO 50965

Sato, Keisuke

Search repository
著者別名
識別子
識別子 50966
識別子Scheme WEKO
姓名
姓名 佐藤, 圭輔
抄録
内容記述タイプ Abstract
内容記述 Background : Understanding of cortico-cortical activity in eloquent areas intraoperatively is crucial for neurosurgical procedures. Here, we used intraoperative near-infrared spectroscopy (iNIRS) during direct cortical stimulation as a robust tool to better understand the cortico-cortical connectivity in language systems.Methods : We applied iNIRS to 3 patients who underwent epilepsy surgery due to lesions (cavernous angioma, epidermoid cyst, and low-grade glioma) located in language areas. Using iNIRS, we measured the blood concentration changes of oxyhemoglobin (HbO2) and deoxyhemoglobin (HbR) in the lateral temporal cortex during direct cortical stimulation (50 Hz) at the inferior frontal area where Broca’s area was probabilistically located.Results : In all patients, 50 Hz stimulation elicited hemodynamic changes in the superior temporal gyrus (STG). During 0.8–4.8 s after stimulation, HbO2 increased and HbR decreased in the posterior part of the STG (Wernicke’s area). Similar responses were observed in the anterior part of the STG 1.3–8.0 s after stimulation. Finally, these changes were disappeared in the middle temporal gyrus.Conclusions : Our results suggest that cortical stimulation of Broca’s area elicits hemodynamic responses in Wernicke's area via cortico-cortical connectivity. We demonstrated cortico-cortical evoked responses in language systems using iNIRS during direct cortical stimulation. Our iNIRS data will provide useful information about cortico-cortical networks underlying human brain functions intraoperatively and will contribute to neurosurgical treatment in eloquent areas.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(医学). 報告番号: 甲第4253号. 学位記番号: 新大院博(医)甲第731号. 学位授与年月日: 平成29年3月23日
内容記述
内容記述タイプ Other
内容記述 Neuroscience Letters 630.136-140,2016
書誌情報 発行日 2017-03-23
出版者
出版者 新潟大学
DOI
関連識別子
識別子タイプ DOI
関連識別子 info:doi/10.1016/j.neulet.2016.07.037
権利
権利情報 © 2016 Elsevier Inc. All rights reserved
著者版フラグ
値 ETD
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2017-03-23
学位授与番号
学位授与番号 13101甲第4253号
学位記番号
内容記述タイプ Other
内容記述 新大院博(医)甲第731号
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