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Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.
http://hdl.handle.net/10191/47573
http://hdl.handle.net/10191/47573a8757ed3-b2bb-4d45-a72a-53402dd91cdc
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要旨 (192.9 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-09-11 | |||||
| タイトル | ||||||
| タイトル | Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer. | |||||
| タイトル | ||||||
| タイトル | Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer. | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | prostate cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | carbon ion radiotherapy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | quality of life | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | prospective study | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_46ec | |||||
| タイプ | thesis | |||||
| その他のタイトル | ||||||
| その他のタイトル | 前立腺癌に対する重粒子線治療後5年間のQOL評価 | |||||
| 著者 |
Maruyama, Katsuya
× Maruyama, Katsuya |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 50947 | |||||
| 姓名 | 丸山, 克也 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The aim of this study was to prospectively assess 5-year health-related quality of life (HRQOL) of patients treated with carbon ion radiotherapy (C-ion RT) for clinically localized prostate cancer. A total of 417 patients received carbon ion radiotherapy at a total dose of 63-66 Gray-equivalents (GyE) in 20 fractions over 5 weeks, and neoadjuvant and adjuvant androgen deprivation therapy (ADT) were administered for intermediate and high-risk patients. A HRQOL assessment was performed at five time points (immediately before the initiation of C-ion RT, immediately after, and at 12, 36 and 60 months after completion of C-ion RT) using Functional Assessment of Cancer Therapy (FACT) questionnaires. FACT-G and FACT-P scores were significantly decreased; however, the absolute change after 60 months was minimal. The transient decreases in the Trial Outcome Index (TOI) score returned to their baseline levels. Use of ADT, presence of adverse events, and biochemical failure were related to lower scores. Scores of subdomains of FACT instruments indicated characteristic changes. The pattern of HRQOL change after C-ion RT was similar to that of other modalities. Further controlled studies focusing on a HRQOL in patients with prostate cancer are warranted. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 学位の種類: 博士（医学）. 報告番号: 甲第4242号. 学位記番号: 新大院博（医）甲第720号. 学位授与年月日: 平成29年3月23日 | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The Journal of Radiation Research 58(2)260-266,2017 | |||||
| 書誌情報 | 発行日 2017-03-23 | |||||
| 出版者 | ||||||
| 出版者 | 新潟大学 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1093/jrr/rrw122 | |||||
| 著者版フラグ | ||||||
| 値 | ETD | |||||
| 学位名 | ||||||
| 学位名 | 博士（医学） | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 新潟大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2017-03-23 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 13101甲第4242号 | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 新大院博（医）甲第720号 | |||||
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Cite as
Maruyama, Katsuya, 2017, Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer.: 新潟大学.
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