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Modulation of excitability of trigeminal neurons during electrical stimulation of the superior laryngeal nerve in anesthetized rabbits
http://hdl.handle.net/10191/42120
http://hdl.handle.net/10191/421204d7a0adb-fd34-43c7-b997-3b9c155482d2
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本文 (433.0 kB)
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要旨 (265.0 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2016-06-16 | |||||
| タイトル | ||||||
| タイトル | Modulation of excitability of trigeminal neurons during electrical stimulation of the superior laryngeal nerve in anesthetized rabbits | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | trigeminal interneuron | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | swallow | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | superior laryngeal nerve | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
| 資源タイプ | thesis | |||||
| その他のタイトル | ||||||
| その他のタイトル | 麻酔下ウサギにおける上喉頭神経刺激時三叉神経ニューロンの興奮性変調 | |||||
| 著者 |
酒井, 翔悟
× 酒井, 翔悟 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The present study investigated the effect of electrical stimulation of the superior laryngeal nerve (SLN) on evoked potentials from trigeminal interneurons. Experiments were carried out on 19 rabbits anesthetized with urethane. Single-unit responses evoked by electrical stimulation of the inferior alveolar nerve were recorded in the trigeminal nucleus. To evoke swallowing reflex, the SLN was electrically stimulated (train pulses; 0.2 ms, 30 Hz). Current intensity of SLN stimulation was set at 2, 4, or 8 times the threshold for evoking swallowing reflex at least once for 10 s. Initiation and change in latency were compared among the periods (before, during, and after SLN stimulation) or among stimulus intensities. Inhibition of evoked responses and delay in latency was observed in 15 of 27 identified neurons (55.6%) and 26/27 (96.3%) neurons, respectively, either during or after SLN stimulation. The rate of inhibition of evoked responses was significantly different among SLN stimulus intensities. Modulated neurons were divided into two groups based on latency, short (< 3 ms) or long (>= 3 ms). Longer latencies resulted in longer delays. Eighteen neurons (66.7%) were found to project to the digastric motor nucleus. Most neurons were distributed in the main sensory trigeminal nucleus or subnucleus-γ of the oral nucleus of the spinal trigeminal tract. These results suggest that sensory information originating from the orofacial region, possibly related to the jaw reflex, was inhibited during or after SLN stimulation possibly by input from the swallowing central pattern generator. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 学位の種類: 博士（歯学）. 報告番号: 甲第4153号. 学位記番号: 新大院博（歯）甲第351号. 学位授与年月日: 平成28年3月23日 | |||||
| 書誌情報 |
発行日 2016-03-23 |
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| 出版者 | ||||||
| 出版者 | 新潟大学 | |||||
| 著者版フラグ | ||||||
| 値 | ETD | |||||
| 学位名 | ||||||
| 学位名 | 博士（歯学） | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 新潟大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2016-03-23 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 13101甲第4153号 | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 新大院博（歯）甲第351号 | |||||
