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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

Prognostic factors and causes of death in patients cured of esophageal cancer.

http://hdl.handle.net/10191/41925
http://hdl.handle.net/10191/41925
9e132912-9d6e-4c96-a465-495faa65894a
名前 / ファイル ライセンス アクション
h27nmk697.pdf 本文 (406.6 kB)
h27nmk697_a.pdf 要旨 (569.9 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2016-05-19
タイトル
タイトル Prognostic factors and causes of death in patients cured of esophageal cancer.
タイトル
言語 en
タイトル Prognostic factors and causes of death in patients cured of esophageal cancer.
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル 食道癌切除後長期生存患者における予後因子と死因についての検討
著者 Kakuta, Tomoyuki

× Kakuta, Tomoyuki

WEKO 50781

Kakuta, Tomoyuki

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著者別名
識別子 50782
識別子Scheme WEKO
姓名 角田, 知行
抄録
内容記述タイプ Abstract
内容記述 Background: The number of patients cured of esophageal cancer after esophagectomy is gradually increasing owning to advances in surgical techniques, perioperative management, and adjuvant therapies. This study assessed the clinical course and sought to identify the prognostic factors of these patients. Methods: A series of 220 consecutive patients who underwent esophagectomy and survived for more than 5 years with no relapse were enrolled. Survival analysis was performed using 25 variables including patient characteristics and operative and perioperative factors. Potential prognostic factors were identified by univariate and multivariate analyses, and the development of other primary cancers and the causes of death were retrospectively reviewed. Results: The overall 10-, 15-, and 20-year survival rates were 71.6, 50.1, and 32.2%, respectively, with a median survival time of 180 months (range, 61–315 months). The negative independent prognostic factors identified were age at surgery (hazard ratio[HR], 1.05;P<0.01), being male (HR, 2.62; P=0.02), pulmonary comorbidities (HR, 2.03; P=0.02), synchronous presence of other cancers (HR, 2.35; P<0.01), colonic/jejunal interposition (HR, 1.76; P=0.03), perioperative blood transfusion (HR, 1.92; P=0.02), development of pulmonary complications (HR, 1.71; P=0.02), and adjuvant radiotherapy (HR, 2.13; P=0.01). Pulmonary diseases and other primary cancers were found to be the most common causes of death. Conclusions: Careful follow up including the surveillance of other primary cancers is required for long-term survivors of esophageal cancer after esophagectomy.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(医学). 報告番号: 甲第4130号. 学位記番号: 新大院博(医)甲第697号. 学位授与年月日: 平成28年3月23日
内容記述
内容記述タイプ Other
内容記述 Annals of Surgical Oncology. 2014, 21(5), 1749-1755.
書誌情報 p. 1-26, 発行日 2016-03-23
出版者
出版者 新潟大学
DOI
識別子タイプ DOI
関連識別子 info:doi/10.1245/s10434-014-3499-7
権利
権利情報 The final publication is available at Springer via http://dx.doi.org/10.1245/s10434-014-3499-7
著者版フラグ
値 ETD
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2016-03-23
学位授与番号
学位授与番号 13101甲第4130号
学位記番号
内容記述タイプ Other
内容記述 新大院博(医)甲第697号
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