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Changes in the frequency of swallowing during electrical stimulation of superior laryngeal nerve in rats
http://hdl.handle.net/10191/32184
http://hdl.handle.net/10191/321840ee59d0d-23a5-41dc-ab78-e72839b4c340
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本文 (976.2 kB)
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要旨 (200.1 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2015-05-28 | |||||
タイトル | ||||||
タイトル | Changes in the frequency of swallowing during electrical stimulation of superior laryngeal nerve in rats | |||||
タイトル | ||||||
タイトル | Changes in the frequency of swallowing during electrical stimulation of superior laryngeal nerve in rats | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Swallowing | |||||
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主題Scheme | Other | |||||
主題 | Superior laryngeal nerve | |||||
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主題Scheme | Other | |||||
主題 | Rat | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Central pattern generator | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nucleus tractus solitarii | |||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
資源タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | ラット上喉頭神経電気刺激中における嚥下頻度の変化 | |||||
著者 |
Tsuji, Kojun
× Tsuji, Kojun |
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著者別名 | ||||||
識別子Scheme | WEKO | |||||
識別子 | 50583 | |||||
姓名 | 辻, 光順 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of the present study was to investigate the adaptation of the swallowing reflex in terms of reduced swallowing reflex initiation following continuous superior laryngeal nerve stimulation. Forty-four male Sprague Dawley rats were anesthetized with urethane. To identify swallowing, electromyographic activity of the left mylohyoid and thyrohyoid muscles was recorded. To evoke the swallowing response, the superior laryngeal nerve (SLN), recurrent laryngeal nerve, or cortical swallowing area was electrically stimulated. Repetitive swallowing evoked by continuous SLN stimulation was gradually reduced, and this reduction was dependent on the resting time duration between stimulations. Prior SLN stimulation also suppressed subsequent swallowing initiation. The reduction in evoked swallows induced by recurrent laryngeal nerve or cortical swallowing area stimulation was less than that following superior laryngeal nerve stimulation. Decerebration had no effect on the reduction in evoked swallows. Prior subthreshold stimulation reduced subsequent initiation of swallowing, suggesting that there was no relationship between swallowing movement evoked by prior stimulation and the subsequent reduction in swallowing initiation. Overall, these data suggest that reduced sensory afferent nerve firing and/or trans-synaptic responses, as well as part of the brainstem central pattern generator, are involved in adaptation of the swallowing reflex following continuous stimulation of swallow-inducing peripheral nerves and cortical areas. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 学位の種類: 博士(歯学). 報告番号: 甲第4015号. 学位記番号: 新大院博(歯)甲第328号. 学位授与年月日: 平成27年3月23日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Brain Research Bulletin. 2015, 111, 53-61. | |||||
書誌情報 | 発行日 2015-03-23 | |||||
出版者 | ||||||
出版者 | 新潟大学 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1016/j.brainresbull.2014.12.008 | |||||
権利 | ||||||
権利情報 | Copyright (C) 2014 Elsevier | |||||
著者版フラグ | ||||||
値 | ETD | |||||
学位名 | ||||||
学位名 | 博士(歯学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 新潟大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2015-03-23 | |||||
学位授与番号 | ||||||
学位授与番号 | 13101甲第4015号 | |||||
学位記番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新大院博(歯)甲第328号 |