{"_buckets": {"deposit": "2754656d-bc88-4b26-ad1c-d8fca0ab15fc"}, "_deposit": {"id": "5386", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "5386"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00005386"}, "item_6_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "\u7cbe\u5de3\u816b\u760d\u75c5\u671fI\u306b\u304a\u3051\u308b\u6cbb\u7642\u6210\u7e3e : \u75c5\u7406\u7d44\u7e54\u5b66\u7684\u30ea\u30b9\u30af\u56e0\u5b50\u304a\u3088\u3073\u8853\u5f8c\u7121\u6cbb\u7642\u7d4c\u904e\u89b3\u5bdf\u306e\u59a5\u5f53\u6027\u306b\u3064\u3044\u3066\u306e\u691c\u8a0e"}]}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-09-20", "bibliographicIssueDateType": "Issued"}, "bibliographic_titles": [{}]}]}, "item_6_date_granted_51": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5", "attribute_value_mlt": [{"subitem_dategranted": "2013-09-20"}]}, "item_6_degree_grantor_49": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u6a5f\u95a2", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "\u65b0\u6f5f\u5927\u5b66"}]}]}, "item_6_degree_name_48": {"attribute_name": "\u5b66\u4f4d\u540d", "attribute_value_mlt": [{"subitem_degreename": "\u535a\u58eb\uff08\u533b\u5b66\uff09"}]}, "item_6_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Background: Surveillance after orchiectomy has recently been a management option in patients with stage I seminoma, while it remains controversial in those with stage I nonseminoma, and the risk factor associated with relapse is still a matter of concern in both entities. This study was performed to explore pathological risk factors for post-orchiectomy relapse in patients with stage I seminoma and nonseminoma, and to assess oncological outcomes in those managed with surveillance. Methods: In this single institution study, 118 and 40 consecutive patients with stage I seminoma and nonseminoma were reviewed, respectively. Of the 118 patients with stage I seminoma, 56 and one received adjuvant radiotherapy and chemotherapy, respectively, and 61 were managed with surveillance. Of the 40 men with stage I nonseminoma, 4 underwent adjuvant chemotherapy and 36 were managed with surveillance. Results: No patient had cause-specific death during the mean observation period of 104 and 99 months in men with seminoma and nonseminoma, respectively. In men with stage I seminoma, 1 (1.7%) receiving radiotherapy and 4 (6.6%) men managed with surveillance had disease relapse; the 10-year relapse-free survival (RFS) rate was 93.4% in men managed with surveillance, and their RFS was not different from that in patients receiving adjuvant radiotherapy (logrank P=0.15). Patients with tunica albuginea involvement showed a poorer RFS than those without (10-year RFS rate 80.0% vs. 94.1%), although the difference was of borderline significance (P=0.09). In men with stage I nonseminoma, 9 (22.5%) patients experienced relapse. Patients with lymphovascular invasion seemingly had a poorer RFS than those without; 40.0% and 18.7% of the patients with and without lymphovascular invasion had disease relapse, respectively, although the difference was not significant (logrank P=0.17). Conclusion: In both men with stage I seminoma and nonseminoma, surveillance after orchiectomy is a feasible option. However, disease extension through tunica albuginea might be a factor associated with disease relapse in patients with organ-confined seminoma, and those with stage I nonseminoma showing lymphovascular invasion may possibly be at high risk for disease relapse.", "subitem_description_type": "Abstract"}]}, "item_6_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u5b66\u4f4d\u306e\u7a2e\u985e: \u535a\u58eb\uff08\u533b\u5b66\uff09. \u5831\u544a\u756a\u53f7: \u4e59\u7b2c2174\u53f7. \u5b66\u4f4d\u8a18\u756a\u53f7: \u65b0\u5927\u535a\uff08\u533b\uff09\u4e59\u7b2c1770\u53f7. \u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5: \u5e73\u621025\u5e749\u670820\u65e5", "subitem_description_type": "Other"}, {"subitem_description": "Diagnostic Pathology. 2013, 8:57", "subitem_description_type": "Other"}]}, "item_6_description_53": {"attribute_name": "\u5b66\u4f4d\u8a18\u756a\u53f7", "attribute_value_mlt": [{"subitem_description": 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"item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kobayashi, Kazuhiro"}], "nameIdentifiers": [{"nameIdentifier": "50185", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-05"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "h25nmo1770.pdf", "filesize": [{"value": "482.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 482600.0, "url": {"label": "\u672c\u6587", "url": "https://niigata-u.repo.nii.ac.jp/record/5386/files/h25nmo1770.pdf"}, "version_id": "fc8be7dc-3464-4b28-865f-f6207398493d"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-05"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "h25nmo1770_a.pdf", "filesize": [{"value": "210.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 210700.0, "url": {"label": "\u8981\u65e8", "url": "https://niigata-u.repo.nii.ac.jp/record/5386/files/h25nmo1770_a.pdf"}, "version_id": "4d4f1897-2c84-4180-93ce-9444ade9231c"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Stage I seminoma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Stage I nonseminoma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Surveillance", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Outcome", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "Oncological outcomes in patients with stage I testicular seminoma and nonseminoma : pathological risk factors for relapse and feasibility of surveillance after orchiectomy", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Oncological outcomes in patients with stage I testicular seminoma and nonseminoma : pathological risk factors for relapse and feasibility of surveillance after orchiectomy"}, {"subitem_title": "Oncological outcomes in patients with stage I testicular seminoma and nonseminoma : pathological risk factors for relapse and feasibility of surveillance after orchiectomy", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["453/455", "471/561/562"], "permalink_uri": "http://hdl.handle.net/10191/24542", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2014-05-28"}, "publish_date": "2014-05-28", "publish_status": "0", "recid": "5386", "relation": {}, "relation_version_is_last": true, "title": ["Oncological outcomes in patients with stage I testicular seminoma and nonseminoma : pathological risk factors for relapse and feasibility of surveillance after orchiectomy"], "weko_shared_id": 2}