{"_buckets": {"deposit": "2f7625bd-5cfe-4e62-8154-f4c32c6e07b6"}, "_deposit": {"id": "4397", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "4397"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00004397", "sets": ["455", "562"]}, "item_6_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Effects in central catecholamine system by nicotine and nicotinic acetylcholine receptor"}]}, "item_6_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-06-06", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "38", "bibliographicPageStart": "1", "bibliographic_titles": [{}]}]}, "item_6_date_granted_51": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "1991-06-06"}]}, "item_6_degree_grantor_49": {"attribute_name": "学位授与機関", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "新潟大学"}]}]}, "item_6_degree_name_48": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "博士（医学）"}]}, "item_6_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We observed the efficacy of cigarette smoking on familial juvenile parkinsonian patients, and considered this efficacy to nicotinic action in the CNS. We tried to confirm the nicotinic function in the rat striatum by means of in vivo microdialysis method, and examined the changes of 3H-nicotine bindings of model rats having lesion of unilateral substantianigra following 6-OHDA injection using the method of macroautoradiography. As a result, DOPAC and HVA values following systemic nicotine injection were elevated statistically comparing to the injection of saline, and radioactivities of 3H-nicotine of lesioned side in striatum, accumbens nucleus, olfactory tubercle weree decreaed statistically comparing to that of non-lesioned side. From these results nicotine and nicotinic acetylcholine recepter are supposed to be closely related to the catecholamine system in the CNS.", "subitem_description_type": "Abstract"}]}, "item_6_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "学位の種類: 博士（医学）. 報告番号: 乙第1155号. 学位記番号: 新大医博乙第1074号. 学位授与年月日: 平成3年6月6日", "subitem_description_type": "Other"}, {"subitem_description": "新潟医学会雑誌. 1991, 105(10), 696-706.", "subitem_description_type": "Other"}]}, "item_6_description_53": {"attribute_name": "学位記番号", "attribute_value_mlt": [{"subitem_description": "新大医博乙第1074号", "subitem_description_type": "Other"}]}, "item_6_dissertation_number_52": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13101B1155"}]}, "item_6_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "48375", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ishikawa, Atsushi"}]}]}, "item_6_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟大学"}]}, "item_6_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "石川, 厚"}], "nameIdentifiers": [{"nameIdentifier": "48374", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-05"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "000000241906.pdf", "filesize": [{"value": "3.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 3200000.0, "url": {"label": "本文", "url": "https://niigata-u.repo.nii.ac.jp/record/4397/files/000000241906.pdf"}, "version_id": "5d3b9c54-cd40-4a4f-8b13-7c145b81fc9d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "nicotine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nicotinic acetylcholine receptor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "catecholamine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "microdialysis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "autoradiography", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ニコチン", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ニコチン性アセチルコリン受容体", "subitem_subject_scheme": "Other"}, {"subitem_subject": "カテコラミン", "subitem_subject_scheme": "Other"}, {"subitem_subject": "マイクロダイアリス", "subitem_subject_scheme": "Other"}, {"subitem_subject": "オートラジオグラフィー", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "中枢神経系におけるカテコラミン系に及ぼすニコチンとニコチン性アセチルコリン受容体の役割", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "中枢神経系におけるカテコラミン系に及ぼすニコチンとニコチン性アセチルコリン受容体の役割"}, {"subitem_title": "中枢神経系におけるカテコラミン系に及ぼすニコチンとニコチン性アセチルコリン受容体の役割", "subitem_title_language": "en"}]}, "item_type_id": "6", "owner": "1", "path": ["455", "562"], "permalink_uri": "http://hdl.handle.net/10191/23775", "pubdate": {"attribute_name": "公開日", "attribute_value": "2013-10-10"}, "publish_date": "2013-10-10", "publish_status": "0", "recid": "4397", "relation": {}, "relation_version_is_last": true, "title": ["中枢神経系におけるカテコラミン系に及ぼすニコチンとニコチン性アセチルコリン受容体の役割"], "weko_shared_id": 2}