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We tried to confirm the nicotinic function in the rat striatum by means of in vivo microdialysis method, and examined the changes of 3H-nicotine bindings of model rats having lesion of unilateral substantianigra following 6-OHDA injection using the method of macroautoradiography. As a result, DOPAC and HVA values following systemic nicotine injection were elevated statistically comparing to the injection of saline, and radioactivities of 3H-nicotine of lesioned side in striatum, accumbens nucleus, olfactory tubercle weree decreaed statistically comparing to that of non-lesioned side. From these results nicotine and nicotinic acetylcholine recepter are supposed to be closely related to the catecholamine system in the CNS.", "subitem_description_type": "Abstract"}]}, "item_6_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u5b66\u4f4d\u306e\u7a2e\u985e: \u535a\u58eb\uff08\u533b\u5b66\uff09. \u5831\u544a\u756a\u53f7: \u4e59\u7b2c1155\u53f7. \u5b66\u4f4d\u8a18\u756a\u53f7: \u65b0\u5927\u533b\u535a\u4e59\u7b2c1074\u53f7. \u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5: \u5e73\u62103\u5e746\u67086\u65e5", "subitem_description_type": "Other"}, {"subitem_description": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c. 1991, 105(10), 696-706.", "subitem_description_type": "Other"}]}, "item_6_description_53": {"attribute_name": "\u5b66\u4f4d\u8a18\u756a\u53f7", "attribute_value_mlt": [{"subitem_description": "\u65b0\u5927\u533b\u535a\u4e59\u7b2c1074\u53f7", "subitem_description_type": "Other"}]}, 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