{"_buckets": {"deposit": "461d0394-5eb7-483d-b5ef-4b7eb42b18f2"}, "_deposit": {"id": "34039", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "34039"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00034039", "sets": ["455", "562"]}, "item_6_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "日本人男性における耐糖能障害と心血管疾患の既往がその後の心血管疾患発症へ与えるの影響の検討"}]}, "item_6_date_granted_51": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "2020-03-23"}]}, "item_6_degree_grantor_49": {"attribute_name": "学位授与機関", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "新潟大学"}]}]}, "item_6_degree_name_48": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "博士(医学)"}]}, "item_6_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Objective: Although glucose abnormality status (GAS), prior coronary artery disease (CAD). , and other traditional risk factors affect the incidence of subsequent CAD, their impact in the same cohort has been scantly studied. Research design and methods: We analyzed data from a nationwide claims database in Japan that was accumulated during 2008–2016 involving 138,162 men aged 18–72 years. Participants were classified as having normoglycemia, borderline glycemia, or diabetes mellitus (DM) with prior CAD (CAD+) or without prior CAD (CAD−). Cox regression model identified variables related to the incidence of CAD. Results: Among CAD−, management of traditional risks differed from those with and without subsequent CAD events. On the other hand, such differences were weaker in borderline glycemia and DM CAD+, and the influence of traditional risk factors on subsequent CAD was not observed. Cox regression model showed that borderline glycemia and DM confer approximately 1.2- and 2.8-fold excess risks of CAD, respectively, compared with CAD− with normoglycemia. CAD+ confers approximately a 5- to 8-fold increased risk. The impacts of DM and prior CAD additively reached a hazard ratio (HR) of 15.74 (95% confidence interval [CI]: 11.82–21.00). However, the HR in those with borderline glycemia and CAD+ was 7.20 (95% CI: 5.01–10.34), which was not different from those with normoglycemia and CAD+. Conclusion: Control status of traditional risk factors and impact on subsequent CAD differ among categories of glycemic status with and without prior CAD. Individualizing treatment strategies is needed in consideration of risk factors, such as GAS and CAD+.", "subitem_description_type": "Abstract"}]}, "item_6_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "Metabolism Clinical and Experimental. 2019, 101, 153991.", "subitem_description_type": "Other"}]}, "item_6_description_53": {"attribute_name": "学位記番号", "attribute_value_mlt": [{"subitem_description": "新大院博(医)甲第948号", "subitem_description_type": "Other"}]}, "item_6_dissertation_number_52": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "13101甲第4714号"}]}, "item_6_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "178077", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "北澤, 勝"}]}]}, "item_6_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.1016/j.metabol.2019.153991", "subitem_relation_type_select": "DOI"}}]}, "item_6_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "【○!C】 2019 Elsevier Inc. All rights reserved."}]}, "item_6_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "ETD"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kitazawa, Masaru"}], "nameIdentifiers": [{"nameIdentifier": "178076", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-08-31"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "r1nmk948.pdf", "filesize": [{"value": "264.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 264400.0, "url": {"label": "本文", "url": "https://niigata-u.repo.nii.ac.jp/record/34039/files/r1nmk948.pdf"}, "version_id": "a0013929-c14b-43f2-aab3-ceae161eb780"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-08-31"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "r1nmk948_a.pdf", "filesize": [{"value": "573.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 573300.0, "url": {"label": "要旨", "url": "https://niigata-u.repo.nii.ac.jp/record/34039/files/r1nmk948_a.pdf"}, "version_id": "88b58067-02d0-49ba-81e2-d02e74a7797f"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Coronary artery disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Glucose abnormality status", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Clinical epidemiology", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cardiovascular disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Risk factors", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "Risk of coronary artery disease according to glucose abnormality status and prior coronary artery disease in Japanese men", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Risk of coronary artery disease according to glucose abnormality status and prior coronary artery disease in Japanese men"}]}, "item_type_id": "6", "owner": "1", "path": ["455", "562"], "permalink_uri": "http://hdl.handle.net/10191/00051837", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-08-31"}, "publish_date": "2020-08-31", "publish_status": "0", "recid": "34039", "relation": {}, "relation_version_is_last": true, "title": ["Risk of coronary artery disease according to glucose abnormality status and prior coronary artery disease in Japanese men"], "weko_shared_id": null}