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Characterization of low adherence population in asthma patients from Japan using Adherence Starts with Knowledge-12
http://hdl.handle.net/10191/00051812
http://hdl.handle.net/10191/0005181260aecc5f-ca16-460b-8b68-899302ef4e0e
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本文 (332.1 kB)
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要旨 (574.9 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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| 公開日 | 2020-08-31 | |||||
| タイトル | ||||||
| タイトル | Characterization of low adherence population in asthma patients from Japan using Adherence Starts with Knowledge-12 | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Bronchial asthma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Adherence starts with Knowledge-12 (ASK12) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Questionnaire survey | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Depression status | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Working status | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
| 資源タイプ | thesis | |||||
| その他のタイトル | ||||||
| その他のタイトル | Adherence Starts with Knowledge-12(ASK-12)による日本における低アドヒアランス気管支喘息患者の特徴 | |||||
| 著者 |
Kimura, Yuka
× Kimura, Yuka |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 178028 | |||||
| 姓名 | 木村, 夕香 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Adherence Starts with Knowledge-12 (ASK-12) is a useful indicator of drug adherence. In this study, we analyzed patient background including social and psychological factors in a low-adherence group of patients with asthma defined using ASK-12. Methods: From a questionnaire survey for patients with asthma from the Niigata Prefecture, Japan, conducted in the fall of 2016, we enrolled patients who answered all ASK-12 items and underwent a measured respiratory function test within 1 year. The low-adherence group (ASK-12 28) was compared with the control group (ASK-12 < 28), and we conducted a cluster analysis of the low-adherence group. Results: There were 170 patients in the low-adherence group and 402 patients in the control group. There was a significant difference between age, gender, working status, smoking history, the percentage of forced expiratory volume in one second (%FEV_1), asthma control test (ACT), and Patient HealthQuestionnaire-9 (PHQ-9). score between the two groups. Logistic analysis revealed that working status (working), % FEV1 (< 90%), and PHQ-9 score (> 5) were independent factors for the low-adherence group. The cluster analysis identified three clusters in the low-adherence group. Among these, one cluster was characterized by elderly males with chronic obstructive pulmonary disease and another by middle-aged nonsmoking females with a depression tendency, had problems with asthma control. Conclusions: Several factors were considered to be attributed to low drug-adherence. There were several phenotypes in the low-adherence population correlated with incomplete asthma control. Intervention with drug adherence should be a future goal for asthma treatment. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Allergology International. 2020, 69(1), 61-65. | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1016/j.alit.2019.07.006 | |||||
| 権利 | ||||||
| 権利情報 | 【○!C】 2019, Japanese Society of Allergology. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||
| 著者版フラグ | ||||||
| 値 | ETD | |||||
| 学位名 | ||||||
| 学位名 | 博士(医学) | |||||
| 学位授与機関 | ||||||
| 学位授与機関名 | 新潟大学 | |||||
| 学位授与年月日 | ||||||
| 学位授与年月日 | 2020-03-23 | |||||
| 学位授与番号 | ||||||
| 学位授与番号 | 13101甲第4689号 | |||||
| 学位記番号 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 新大院博(医)甲第923号 | |||||
