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Vascular Hyperintensity on Fluid-Attenuated Inversion Recovery Indicates the Severity of Hypoperfusion in Acute Stroke
http://hdl.handle.net/10191/00051793
http://hdl.handle.net/10191/000517938d84e707-f53f-4373-9055-339e634679d7
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2020-08-31 | |||||
タイトル | ||||||
タイトル | Vascular Hyperintensity on Fluid-Attenuated Inversion Recovery Indicates the Severity of Hypoperfusion in Acute Stroke | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Ischemic stroke | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | brain infarction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | magnetic resonance imaging | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | magnetic resonance angiography | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | perfusion imaging | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | 急性期脳梗塞におけるFluid-attenuated inversion recovery (FLAIR) 画像上の血管高信号は灌流低下の重症度を反映する | |||||
著者 |
Nomura, Toshiharu
× Nomura, Toshiharu |
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著者別名 | ||||||
識別子 | 177990 | |||||
識別子Scheme | WEKO | |||||
姓名 | 野村, 俊春 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background and Aim: Although fluid-attenuated inversion recovery vascular hyperintensities may be frequently seen in acute large-artery ischemic stroke, reports on their prognostic utility had been conflicting due to lack of quantitative evaluation of the perfusion status based on the signal intensity. We hypothesized that greater hyper intensity represents more severe hypoperfusion. Methods: Overall, 27 patients with acute occlusion of the proximal middle cerebral artery were divided into 2 groups, based on their signal intensity in the insular segment of middle cerebral artery on the affected side, relative to that of the insular cortex: the low signal intensity group (hypo- or isointense signals, n = 12) and the high signal intensity group (hyperintense signals, n = 15). Using dynamic susceptibility contrast magnetic resonance imaging, we assessed the time of the maximum value of the residue function and mean transit time, in the entire middle cerebral artery cortical area and diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score regions, including the corona radiata. Results: The high signal intensity group had significantly longer time of the maximum value of the residue function in all the diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score regions, except the M3 and M6 regions, and significantly longer mean transit time in the M1 and M4regions. Conclusions: Quantitative analysis of the perfusion parameters revealed more severely compromised and widely disturbed perfusion status in the high signal intensity group than in the low signal intensity group. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Stroke and Cerebrovascular Diseases. 2020, 29(2), 104467. | |||||
書誌情報 | p. 1-8 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1016/j.jstrokecerebrovasdis.2019.104467 | |||||
権利 | ||||||
権利情報 | 【○!C】 2019 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/) | |||||
著者版フラグ | ||||||
値 | ETD | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 新潟大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2020-03-23 | |||||
学位授与番号 | ||||||
学位授与番号 | 13101甲第4670号 | |||||
学位記番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新大院博(医)甲第904号 |