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Methods: This cross-sectional study included 1276 RA outpatients from two hospitals. The Roland–Morris Disability Questionnaire was used to address the functional–dysfunctional state criterion. Clinical variables, such as medical status, disease activity, bone mineral density, and spinopelvic alignment parameters, were compared between patients with and without dysfunctional LBP. Results: Mean age and disease duration were 64.6 and 13.4 years, respectively; the prevalence of dysfunctional LBP was 32.8%. On univariate analysis, significant differences existed in many variables, except sex, body weight, C-reactive protein (CRP) level, and prevalence of biological agent users, between patients with and without dysfunctional LBP. 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Prevalence of and factors associated with dysfunctional low back pain in patients with rheumatoid arthritis
http://hdl.handle.net/10191/00051717
http://hdl.handle.net/10191/000517173e9e0907-dad5-46f6-80db-acfa0043bd39
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2020-07-08 | |||||
タイトル | ||||||
タイトル | Prevalence of and factors associated with dysfunctional low back pain in patients with rheumatoid arthritis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rheumatoid arthritis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Low back pain | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Body mass index | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Spinopelvic malalignment | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Vertebral fractures | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Methotrexate | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_46ec | |||||
タイプ | thesis | |||||
その他のタイトル | ||||||
その他のタイトル | 関節リウマチ症例における機能障害性腰痛の頻度と関連する因子 | |||||
著者 |
Miura, Kazuto
× Miura, Kazuto |
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著者別名 | ||||||
識別子 | 177883 | |||||
識別子Scheme | WEKO | |||||
姓名 | 三浦, 一人 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: To investigate the prevalence of and factors associated with dysfunctional low back pain (LBP) in patients with rheumatoid arthritis (RA). Methods: This cross-sectional study included 1276 RA outpatients from two hospitals. The Roland–Morris Disability Questionnaire was used to address the functional–dysfunctional state criterion. Clinical variables, such as medical status, disease activity, bone mineral density, and spinopelvic alignment parameters, were compared between patients with and without dysfunctional LBP. Results: Mean age and disease duration were 64.6 and 13.4 years, respectively; the prevalence of dysfunctional LBP was 32.8%. On univariate analysis, significant differences existed in many variables, except sex, body weight, C-reactive protein (CRP) level, and prevalence of biological agent users, between patients with and without dysfunctional LBP. Multivariate logistic regression analysis revealed body mass index (BMI; odds ratio [OR], 1.116; P<0.001), onset age of RA (OR, 1.020; P=0.020), disease duration of RA (OR, 1.043; P<0.001), methotrexate (MTX) use (OR, 0.609; P=0.007), vertebral fractures (OR, 2.189; P=0.001), vertebral endplate and/or facet erosion (OR, 1.411; P=0.043), disease activity score (DAS) in 28 joints-CRP (DAS-28CRP) (OR, 1.587; P=0.001), pelvic tilt (PT; OR, 1.023; P=0.019), and sagittal vertical axis (SVA; OR, 1.007; P=0.043) as associated factors. Conclusion: The factors associated with dysfunctional LBP in patients with RA were more vertebral fractures, higher DAS28CRP, vertebral endplate and/or facet erosion, higher BMI, longer disease duration, greater PT, older onset age, greater SVA, and less MTX use. Strictly controlling patients’ body weight and disease activity with MTX and avoiding spinopelvic malalignment through vertebral fracture prevention are important. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | European Spine Journal. 2019, 28(5), 976-982. | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1007/s00586-019-05938-x | |||||
権利 | ||||||
権利情報 | 【○!C】 The Author(s) 2019 | |||||
著者版フラグ | ||||||
値 | ETD | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 新潟大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2019-09-20 | |||||
学位授与番号 | ||||||
学位授与番号 | 13101甲第4636号 | |||||
学位記番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 新大院博(医)甲第896号 |