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  1. 260 大学院医歯学総合研究科(歯)
  2. 60 博士学位論文
  3. 10 博士学位論文
  1. 0 資料タイプ別
  2. 02 学位論文

Sox Genes Show Spatiotemporal Expression during Murine Tongue and Eyelid Development

http://hdl.handle.net/10191/51347
http://hdl.handle.net/10191/51347
f0a76763-1842-441b-870f-2b93ec9e2521
名前 / ファイル ライセンス アクション
h30ndk421.pdf 本文 (25.0 MB)
h30ndk421_a 要旨 (322.0 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2019-07-10
タイトル
タイトル Sox Genes Show Spatiotemporal Expression during Murine Tongue and Eyelid Development
タイトル
言語 en
タイトル Sox Genes Show Spatiotemporal Expression during Murine Tongue and Eyelid Development
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_46ec
タイプ thesis
その他のタイトル
その他のタイトル Sox遺伝子群は舌と目蓋の発生において、時空的な発現を示す
著者 Ishikawa, Ryuichi

× Ishikawa, Ryuichi

WEKO 175231

Ishikawa, Ryuichi

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著者別名
識別子 175232
識別子Scheme WEKO
姓名 石川, 隆一
抄録
内容記述タイプ Abstract
内容記述 The tongue is a critical organ, involved in functions such as speaking, swallowing, mastication, and degustation. Although Sox genes are known to play critical roles in many biological processes, including organogenesis, the expression of the Sox family members during tongue development remains unclear. We therefore performed a comparative in situ hybridization analysis of 17 Sox genes (Sox1–14, 17, 18, and 21) during murine tongue development. Sox2, 4, 6, 8, 9, 10, 11, 12, and 21 were found to be expressed in the tongue epithelium, whereas Sox2, 4–6, 8–11, 13, and 21 showed expression in the mesenchyme of the developing tongue. Expression of Sox1, 4, 6, 8–12, and 21 were observed in the developing tongue muscle. Sox5 and 13 showed expression only at E12, while Sox1 expression was observed only on E18. Sox6, 8, 9, and 12 showed expression at several stages. Although the expression of Sox2, 4, 10, 11, and 21 was detected during all the four stages of tongue development, their expression patterns differed among the stages. We thus identified a dynamic spatiotemporal expression pattern of the Sox genes during murine tongue development. To understand whether Sox genes are involved in the development of other craniofacial organs through similar roles to those in tongue development, we also examined the expression of Sox genes in eyelid primordia, which also contain epithelium, mesenchyme, and muscle. However, expression patterns and timing of Sox genes differed between tongue and eyelid development. Sox genes are thus related to organogenesis through different functions in each craniofacial organ.
内容記述
内容記述タイプ Other
内容記述 学位の種類: 博士(歯学). 報告番号: 甲第4572号. 学位記番号: 新大院博(歯)甲第421号. 学位授与年月日: 平成31年3月25日
内容記述
内容記述タイプ Other
内容記述 International Journal of Dentistry. 2018
書誌情報 p. 1-13, 発行日 2019-03-25
出版者
出版者 新潟大学
DOI
識別子タイプ DOI
関連識別子 info:doi/10.1155/2018/1601363
権利
権利情報 Copyright 【○!C】 2018 Ryuichi Ishikawa et al.
著者版フラグ
値 ETD
学位名
学位名 博士(歯学)
学位授与機関
学位授与機関名 新潟大学
学位授与年月日
学位授与年月日 2019-03-25
学位授与番号
学位授与番号 13101甲第4572号
学位記番号
内容記述タイプ Other
内容記述 新大院博(歯)甲第421号
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