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  1. 050 理学部
  2. 10 学術雑誌論文
  3. 10 査読済論文
  1. 0 資料タイプ別
  2. 01 学術雑誌論文

Immunohistochemical study on the fetal rat pituitary in hyperthermia-induced exencephaly

http://hdl.handle.net/10191/6257
http://hdl.handle.net/10191/6257
4049c82c-341f-487d-abd2-9b3f5eb191d4
名前 / ファイル ライセンス アクション
08_0003.pdf 08_0003.pdf (865.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2008-04-23
タイトル
言語 en
タイトル Immunohistochemical study on the fetal rat pituitary in hyperthermia-induced exencephaly
言語
言語 eng
キーワード
主題Scheme Other
主題 hyperthermia
キーワード
主題Scheme Other
主題 exencephaly
キーワード
主題Scheme Other
主題 pituitary
キーワード
主題Scheme Other
主題 adrenal atrophy
キーワード
主題Scheme Other
主題 fetal rat
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Watanabe, Yuichi G.

× Watanabe, Yuichi G.

WEKO 38373

en Watanabe, Yuichi G.

Search repository
著者別名
識別子 38374
識別子Scheme WEKO
姓名 渡辺, 勇一
言語 ja
抄録
内容記述タイプ Abstract
内容記述 Hyperthermia of fetal rats is known to cause malformations of various organs including brain. The present study was carried out to investigate the effect of the hyperthermia-induced brain damages on the development of the adenohypophysis. Mother rats of Day 9.5 of pregnancy were anesthetized and immersed in hot water (43℃) for 15 min. At Day 21.5 of gestation, fetuses were removed by caesarian section and examined for exencephaly. Hyperthermal stress induced varying degrees of exencephaly in 36% of surviving fetal rats. In extreme cases a considerable part of head was lost. Even in those fetuses with severe brain deformities, the hypophysial stalk and neural lobe were present though they were markedly underdeveloped. In exencephalic fetuses, no immunoreactive vasopressin was detected in the neural lobe of the hypophysis. Immunohistochemical examination of the adenohypophysis showed that exencephaly caused a marked decrease in the number of growth hormone (GH)-producing cells. Other types of hormone-producing cells appeared to be unaffected by brain anomaly. The reason for a decreased population of GH cells in exencephalic fetuses is discussed in relation to their adrenocortical hypotrophy.
言語 en
書誌情報 en : Zoological Science

巻 19, 号 6, p. 689-694, 発行日 2002
出版者
言語 en
出版者 Zoological Society of Japan
ISSN
収録物識別子タイプ ISSN
収録物識別子 0289-0003
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10545874
DOI
識別子タイプ DOI
関連識別子 http://doi.org/10.2108/zsj.19.689
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
著者版フラグ
値 publisher
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