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"subitem_description_type": "Abstract"}, {"subitem_description": "Many recent reports have shown that oral surgery can be successfully performed for patients undergoing antithrombotic therapy. Since January 2006, we have treated these patients without drug cessation according to our peri-operative manual. In this study, we retrospectively evaluate postoperative bleeding in patients who received antithrombotic therapy in order to select effective procedure to reduce hemorrhagic risk. We also discuss how patient do not need to interrupt antithrombotic therapy for oral surgery. Finally we validated our peri-operative manual for these patients. We assessed 146 antithrombotic therapy cases, which included 137 cases without drug cessation and 9 cases with drug cessation, which had oral surgery between January 2006 and December 2007. A total of 22 of 137 cases (16.6%) without drug cessation required management of postoperative bleeding immediately after surgery. These cases, with significant amount of bleeding characteristic of Warfarin therapy, did not correlate with PT-INR and postoperative bleeding rate. For tooth extraction cases only, an increased number of tooth extraction increased postoperative bleeding. A haemostatic material, suture, or their combination of both diminished postoperative bleeding. There was no recurrence of postoperative bleeding when making full use of routine hemorrhagic control and without blood transfusion. For 2 of 9 cases (22.2%) with drug cessation, we managed postoperative bleeding. We successfully performed using routine hemorrhagic control along with adjustment of the timing for re-starting antithrombotic therapy. In conclusion, to retain our peri-operative manual for oral surgery for patients receiving antithrombotic therapy, there are two factors that may influence security and safety peri-operative management. One is identification of relevant control measures for a previous illness and antithrombotic therapy (including the latest PT-INR) with a medical referral from MD for permission for systemic use. Another factor is a judgment for the possibility of inconsequential postoperative bleeding using a direct procedure to easily obtain local hemorrhagic control. In addition, we should consider the kinds of antithrombotic therapy, wound conditions, mental management, and preparation of the peri-operative environment; these can be used to successfully manage oral surgery.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "149931", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Yamada, Yushi"}]}, {"nameIdentifiers": [{"nameIdentifier": "149932", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kodama, Yasumitsu"}]}, {"nameIdentifiers": [{"nameIdentifier": "149933", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nagata, Masaki"}]}, {"nameIdentifiers": [{"nameIdentifier": "149934", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Hoshina, Hideyuki"}]}, {"nameIdentifiers": [{"nameIdentifier": "149935", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Seo, Kenji"}]}, {"nameIdentifiers": 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