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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第101巻第8号

亜急性小脳変性症における血中抗神経組織抗体の検討

http://hdl.handle.net/10191/36642
http://hdl.handle.net/10191/36642
0cb585cc-abfb-46bf-817e-692b3f05e220
名前 / ファイル ライセンス アクション
101(8)_514-522.pdf 101(8)_514-522.pdf (3.1 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-01-12
タイトル
タイトル 亜急性小脳変性症における血中抗神経組織抗体の検討
タイトル
言語 en
タイトル 亜急性小脳変性症における血中抗神経組織抗体の検討
言語
言語 jpn
キーワード
主題Scheme Other
主題 subacute cerebellar degeneration
キーワード
主題Scheme Other
主題 Lambert-Eaton myasthenic syndrome
キーワード
主題Scheme Other
主題 serum antibody
キーワード
主題Scheme Other
主題 brain proteins
キーワード
主題Scheme Other
主題 immunoblotting
キーワード
主題Scheme Other
主題 亜急性小脳変性症
キーワード
主題Scheme Other
主題 血中抗神経組織抗体
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Antibodies to Brain Proteins in Paraneoplastic Cerebellar Degeneration
著者 田中, 恵子

× 田中, 恵子

WEKO 143863

田中, 恵子

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著者別名
識別子 143864
識別子Scheme WEKO
姓名 Tanaka, Keiko
抄録
内容記述タイプ Abstract
内容記述 This is a report of two patients with subacute cerebellar degeneration associated with cancer whose sera showed antibody activities against nervous tissue elements. Using an immuno-blotting method, the serum of a 68-year-old man with subacute cerebellar degeneration and malignant lymphoma reacted with rat cerebral 250-kd and 110-kd and cerebellar 110-kd acidic cytoplasmic proteins. The serum IgG of the second patient, a 50-year-old woman, who had subacute cerebellar degeneration, Lambert-Eaton myasthenic syndrome and small cell cancer of the lung showed antibody activities to rat cerebral and cerebellar 98-kd neutral cytoplasmic protein and 68-kd membrane protein. These sera did not react with the proteins prepared from human and rat brain obtained several hours after death, which indicated that these antigen proteins were easily degraded and needed to be prepared quickly after death with protease inhibitors. These patients' sera did not react with proteins prepared from rat liver, kidney, spleen, heart muscle and diaphragm and the antigen proteins reacted with these sera might be brain specific. Control sera did not react with any of the brain proteins. The serum of each patients recognized different antigens. Other reported antigens in the literature are also different which indicates those proteins reacting with serum antibody are variable indiviaually among patients with subacute cerebellar degeneration.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 101, 号 8, p. 514-522, 発行日 1987-08
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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