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未熟心筋における心筋保護の特殊性と問題点
http://hdl.handle.net/10191/40857
http://hdl.handle.net/10191/408573517b24b-093a-497c-b55f-be1b5b9857e9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
102(7)_431-444.pdf (2.6 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-04-06 | |||||
| タイトル | ||||||
| タイトル | 未熟心筋における心筋保護の特殊性と問題点 | |||||
| タイトル | ||||||
| タイトル | 未熟心筋における心筋保護の特殊性と問題点 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | neonate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | myocardial protection | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | St. Thomas' solution | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 新生児 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 心筋保護 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | St. Thomas 液 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Insufficient Protection of the Immature Myocardium from Ischemia | |||||
| 著者 |
渡辺, 弘
× 渡辺, 弘 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 141014 | |||||
| 姓名 | Watanabe, Hiroshi | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Effect of ischemia on the mechanical function and metabolism of the ventricular myocardium of newborn guinea pig was investigated in the isolated perfused heart preparation in comparison with that of adult guinea pig. After ischemia, the newborn myocardium showed a better recovery of the mechanical function and a higher ATP content than the adult. However, while cardioplegia by the St. Thomas' Hospital cardioplegic solution resulted in an excellent preservation of the myocardial mechanical and metabolic condition in the adult, the protection was not so marked in the newborn. Myocardial contracture observed in the newborn upon administration of the cardioplegic solution may be a cause of the poorer protection afforded by the cardioplegic solution in the newborn as compared with that in the adult. To elucidate mechanism of the contracture the membrane potential of papillary muscle preparation was recorded by means of conventional glass microelectrodes. There was no significant difference in the control values of resting membrane potential and in the degree of depolarization during exposure to the St Thomas' Hospital cardioplegic solution between newborn preparation and the adult. These results suggested that the greater contracture of the immature myocardium by the St. Thomas' Hospital cardioplegic solution was not due to a greater depolarization produced by the cardioplegic solution. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 102, 号 7, p. 431-444, 発行日 1988-07 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
