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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第103巻第10号

5) モノアミンレセプターと機能精神病(シンポジウム レセプターとその臨床, 第443回新潟医学会)

http://hdl.handle.net/10191/41428
http://hdl.handle.net/10191/41428
951ec45e-7d99-4e65-ac1c-dd66b0a88590
名前 / ファイル ライセンス アクション
103(10)_813-817.pdf 103(10)_813-817.pdf (1.1 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-04-12
タイトル
タイトル 5) モノアミンレセプターと機能精神病(シンポジウム レセプターとその臨床, 第443回新潟医学会)
タイトル
言語 en
タイトル 5) モノアミンレセプターと機能精神病(シンポジウム レセプターとその臨床, 第443回新潟医学会)
言語
言語 jpn
キーワード
主題Scheme Other
主題 monoamine receptor
キーワード
主題Scheme Other
主題 schizophrenia
キーワード
主題Scheme Other
主題 depression
キーワード
主題Scheme Other
主題 モノアミンレセプター
キーワード
主題Scheme Other
主題 精神分裂病
キーワード
主題Scheme Other
主題 うつ病
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Monoamine receptors and functional psychosis(Receptor Diseases)
著者 富樫, 俊二

× 富樫, 俊二

WEKO 137935

富樫, 俊二

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著者別名
識別子 137936
識別子Scheme WEKO
姓名 Togashi, Shunji
抄録
内容記述タイプ Abstract
内容記述 Several lines of evidence link the dopaminergic neurotransmitter system to schizophrenia. The antipsychotic action of neuroleptic drugs is correlated well with the bloekade of D_2 dopamine receptors. Amphetamines, which elevate synaptic dopamine levels, can induce psychotic states resembling schizophrenia. Increased numbers of D_2 dopamine receptors have been reported in vitro radioreceptor assay in postmortem studies and in vivo PET studies of the brains of schizophrenic patients. But, in some studies, these increases were attributed to prior neuroleptic treatment of the patient, while in other PET study increases were not found in schizophrenic patients. Hence, interpsetation of the elevation in dopamine receptor of schizophrenia has remained controversial. Animal studies have shown that all effective antidepressant treatment act to decrease NE-stimulated c-AMP accumulation in the brain. This finding was followed by reports showing that treatment with antidepressant drugs for several days reduced the density of both beta-adrenergic receptor and serotonin_2 receptor in rat cerebral cortex. The chronological parallel between such phenomenon and the clinical efficacy of these drugs suggests that the changes of the function of beta-receptor and serotonin_2 receptor may underlie in the pathogenesis of affective disorders. In this review, I summarized the recent investigations concerning the monoamine receptors and functional psychcosis.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 103, 号 10, p. 813-817, 発行日 1989-10
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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