{"_buckets": {"deposit": "402853de-e100-4f34-9ad3-ddfae4c34dcc"}, "_deposit": {"id": "22763", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22763"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022763", "sets": ["456", "1205"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Anti-Acetylcholine Receptor Antibody and Myasthenia Gravis(Receptor Diseases)"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "800", "bibliographicPageStart": "798", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Anti-acetylcholine receptor (AChR) antibody is highly disease-specific to myasthenia gravis (MG) comparing to other autoimmune disease, and it is rare to detect other autoimmune antibody. Therefore, immune tolerance system of MG seems to be somewhat different from other autoimmune diseases. However, there is a variation in anti-AChR antibody and anti-AChR antibody is not always correlate with clinical severity. AChR is composed of five subunits, two of α and each one of β, γ and δ and has transmembrane stracture. Fifty percent of antibody to native AChR bind to and more than a half of antibody of patient with MG bind to one region, which is called main immunogenic region (MIR) and is located on α subunit. Peptide mapping of each subunit has high homology. Localization of MIR is not established yet. Farther study of MIR, study of AChR using monoclonal antibody to peptid and establishment of antigenic region on AChR are needed.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "137918", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nagai, Hiroko"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "永井, 博子"}], "nameIdentifiers": [{"nameIdentifier": "137917", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "103(10)_798-800.pdf", "filesize": [{"value": "1.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1100000.0, "url": {"label": "103(10)_798-800.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22763/files/103(10)_798-800.pdf"}, "version_id": "a87a4e03-0199-4d33-91e4-bf6fa0afc46d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Myasthenia gravis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-acetylcholine receptor antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "acetylcholine receptor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "peptide map", "subitem_subject_scheme": "Other"}, {"subitem_subject": "重症筋無力症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "抗アセチルコリンレセプター抗体", "subitem_subject_scheme": "Other"}, {"subitem_subject": "アセチルコリンレセプター", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ペプチドマップ", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "2) アセチルコリンレセプター抗体と重症筋無力症(シンポジウム レセプターとその臨床, 第443回新潟医学会)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "2) アセチルコリンレセプター抗体と重症筋無力症(シンポジウム レセプターとその臨床, 第443回新潟医学会)"}, {"subitem_title": "2) アセチルコリンレセプター抗体と重症筋無力症(シンポジウム レセプターとその臨床, 第443回新潟医学会)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1205"], "permalink_uri": "http://hdl.handle.net/10191/41433", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-04-12"}, "publish_date": "2016-04-12", "publish_status": "0", "recid": "22763", "relation": {}, "relation_version_is_last": true, "title": ["2) アセチルコリンレセプター抗体と重症筋無力症(シンポジウム レセプターとその臨床, 第443回新潟医学会)"], "weko_shared_id": null}