ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "28d3feb0-cc61-412b-b2a2-04290b461381"}, "_deposit": {"id": "22042", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22042"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022042", "sets": ["456", "1194"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Alternative Splicing in Myelin-Associated Glycoprotein (MAG) Gene"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1990-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "9", "bibliographicPageEnd": "755", "bibliographicPageStart": "745", "bibliographicVolumeNumber": "104", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The structures of three forms of mouse myelin-associated glycoprotein(MAG) mRNAs were determined from full-length cDNA clones. Two forms of mRNAs have been reported to be different by alternate inclusion of exon 2 and 12 portions in the rat brain. One of the three forms of clones obtained here appeared to be a novel mRNA which lacked both the exon 2 and 12 portions, although others were identical splicing patterns to those of rat. Two polypeptide isoforms of MAG with molecular masses of 72 and 67 kDa are produced by alternative splicing of the exon 12 portion containing a termination codon. Evidence was presented that expression of the two MAG mRNAs was developmentally regulated in the mouse brain. In the quaking mouse, the mRNA without the exon 12 portion coding the large MAG isoform was scarcely expressed throughout development. Specific antibodies to L-MAG and S-MAG respectively were prepared, and immunoblots showed that the L-MAG band was scarcely detectable in the quaking mouse brain, whereas the S-MAG had a higher apparent molecular mass than in the normal control. Immunohistochemical study also showed that L-MAG was not stained in the quaking mouse brain. These results seemed to reflect a reduction in the L-MAG mRNA and abnormal glycosylation in the quaking mouse brain.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "134066", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Fujita, Nobuya"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "藤田, 信也"}], "nameIdentifiers": [{"nameIdentifier": "134065", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "104(9)_745-755.pdf", "filesize": [{"value": "4.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 4099999.9999999995, "url": {"label": "104(9)_745-755.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22042/files/104(9)_745-755.pdf"}, "version_id": "e95e013b-a627-48e7-8fd2-d7b3c7c63c17"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "myelin-associated glycoprotein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "alternative splicing", "subitem_subject_scheme": "Other"}, {"subitem_subject": "quaking mouse", "subitem_subject_scheme": "Other"}, {"subitem_subject": "髄鞘関連糖蛋白", "subitem_subject_scheme": "Other"}, {"subitem_subject": "選択的スプライシング", "subitem_subject_scheme": "Other"}, {"subitem_subject": "髄鞘形成不全マウス", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究"}, {"subitem_title": "Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1194"], "permalink_uri": "http://hdl.handle.net/10191/34669", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-11-23"}, "publish_date": "2015-11-23", "publish_status": "0", "recid": "22042", "relation": {}, "relation_version_is_last": true, "title": ["Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究"], "weko_shared_id": null}
  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第104巻第9号

Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究

http://hdl.handle.net/10191/34669
http://hdl.handle.net/10191/34669
4bb66b46-0654-41c2-ab0b-84b297f46113
名前 / ファイル ライセンス アクション
104(9)_745-755.pdf 104(9)_745-755.pdf (4.1 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-11-23
タイトル
タイトル Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究
タイトル
言語 en
タイトル Myelin-associated Glycoprotein(MAG)遺伝子のAlternative Splicingに関する分子生物学的研究
言語
言語 jpn
キーワード
主題Scheme Other
主題 myelin-associated glycoprotein
キーワード
主題Scheme Other
主題 alternative splicing
キーワード
主題Scheme Other
主題 quaking mouse
キーワード
主題Scheme Other
主題 髄鞘関連糖蛋白
キーワード
主題Scheme Other
主題 選択的スプライシング
キーワード
主題Scheme Other
主題 髄鞘形成不全マウス
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Alternative Splicing in Myelin-Associated Glycoprotein (MAG) Gene
著者 藤田, 信也

× 藤田, 信也

WEKO 134065

藤田, 信也

Search repository
著者別名
識別子 134066
識別子Scheme WEKO
姓名 Fujita, Nobuya
抄録
内容記述タイプ Abstract
内容記述 The structures of three forms of mouse myelin-associated glycoprotein(MAG) mRNAs were determined from full-length cDNA clones. Two forms of mRNAs have been reported to be different by alternate inclusion of exon 2 and 12 portions in the rat brain. One of the three forms of clones obtained here appeared to be a novel mRNA which lacked both the exon 2 and 12 portions, although others were identical splicing patterns to those of rat. Two polypeptide isoforms of MAG with molecular masses of 72 and 67 kDa are produced by alternative splicing of the exon 12 portion containing a termination codon. Evidence was presented that expression of the two MAG mRNAs was developmentally regulated in the mouse brain. In the quaking mouse, the mRNA without the exon 12 portion coding the large MAG isoform was scarcely expressed throughout development. Specific antibodies to L-MAG and S-MAG respectively were prepared, and immunoblots showed that the L-MAG band was scarcely detectable in the quaking mouse brain, whereas the S-MAG had a higher apparent molecular mass than in the normal control. Immunohistochemical study also showed that L-MAG was not stained in the quaking mouse brain. These results seemed to reflect a reduction in the L-MAG mRNA and abnormal glycosylation in the quaking mouse brain.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 104, 号 9, p. 745-755, 発行日 1990-09
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 13:27:49.680545
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3