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Pulpal Regeneration after Cavity Preparation, with special Reference to Close Spatio-relationships between Odontoblasts and Immunocompetent Cells
http://hdl.handle.net/10191/1800
http://hdl.handle.net/10191/1800503465ee-1728-41e8-be2e-b4fad5fa9686
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
9_0007.pdf (124.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2007-05-10 | |||||
| タイトル | ||||||
| タイトル | Pulpal Regeneration after Cavity Preparation, with special Reference to Close Spatio-relationships between Odontoblasts and Immunocompetent Cells | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | class II MHC molecule | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | dental pulp | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | heat shock protein 25 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | tissue reaction | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 著者 |
Ohshima, Hayato
× Ohshima, Hayato× Nakakura-Ohshima, Kuniko× Takeuchi, Kiichi× Hoshino, Masaaki× Takano, Yoshiro× Maeda, Takeyasu |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 14 | |||||
| 姓名 | 大島, 勇人 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The regeneration process of the odontoblast cell layer incident to tooth injury, especially its relationship with immunocompetent cells in pulp healing, has not been fully understood. The purpose of the present study was to clarify this relationship between odontoblasts and immunocompetent cells in the process of pulp regeneration following cavity preparation in rat molars by immunocytochemistry for heat shock protein (Hsp) 25 as well as class II major histocompatibility complex (MHC) molecules. In untreated control teeth, intense Hsp 25-immunoreactivity was found in the cell bodies of odontoblasts and their processes within the predentin, whereas class II MHC-positive cells were predominantly located beneath the odontoblast cell layer. Cavity preparation caused the destruction of the odontoblast layer to form an edematous lesion and the shift of class II MHC-positive cells with the injured odontoblasts toward the pulp core at the affected site. Some damaged odontoblasts without apparent cytoplasmic processes, round in profile, retained the immunoreactivity for Hsp25, suggesting the survival of a part of the odontoblasts against artificial external stimuli. Twelve hours after cavity preparation, numerous class II MHC-positive cells appeared along the pulp-dentin border and extended their processes deep into the exposed dentinal tubules. By postoperative 72 hours, newly-differentiated odontoblasts with Hsp 25-immunoreactivity were arranged at the pulp-dentin border, but the class II MHC-positive cells moved from the pulp-dentin border to the subodontoblastic layer. These findings indicat that the time course of changes in the expression of Hsp 25-immunoreactivity reflects the regeneration process of odontoblasts. The functional roles of Hsp 25-positive odontoblasts and immunocompetent cells such as class II MHC-positive cells in the process of pulp regeneration after cavity preparation are discussed in conjunction with our previous experimental data. | |||||
| 書誌情報 |
Microscopy research and technique en : Microscopy research and technique 巻 60, 号 5, p. 483-490, 発行日 2003-04 |
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| 出版者 | ||||||
| 出版者 | John Wiley & Sons Ltd. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1059910X | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA1082314X | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1002/jemt.10289 | |||||
| 権利 | ||||||
| 権利情報 | Wiley-Liss, INC. | |||||
| 著者版フラグ | ||||||
| 値 | author | |||||
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Cite as
Ohshima, Hayato, Nakakura-Ohshima, Kuniko, Takeuchi, Kiichi, Hoshino, Masaaki, Takano, Yoshiro, Maeda, Takeyasu, 2003, Pulpal Regeneration after Cavity Preparation, with special Reference to Close Spatio-relationships between Odontoblasts and Immunocompetent Cells: John Wiley & Sons Ltd., 483–490 p.
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