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  1. 0 資料タイプ別
  2. 01 学術雑誌論文
  1. 300 医歯学総合病院
  2. 10 学術雑誌論文
  3. 10 査読済論文

Masked MLL gene rearrangement was disclosed in the clinical course and sequential development of chromosone abnormality in a patient with therapy related acute myelogeneous leukemia

http://hdl.handle.net/10191/1172
http://hdl.handle.net/10191/1172
45ba78f0-5f69-469b-9b38-cb24ae6e2d43
名前 / ファイル ライセンス アクション
24_0016.pdf 24_0016.pdf (723.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-04-23
タイトル
タイトル Masked MLL gene rearrangement was disclosed in the clinical course and sequential development of chromosone abnormality in a patient with therapy related acute myelogeneous leukemia
タイトル
タイトル Masked MLL gene rearrangement was disclosed in the clinical course and sequential development of chromosone abnormality in a patient with therapy related acute myelogeneous leukemia
言語 en
言語
言語 eng
キーワード
主題Scheme Other
主題 MLL
キーワード
主題Scheme Other
主題 t(9;11)
キーワード
主題Scheme Other
主題 secondary leukemia
キーワード
主題Scheme Other
主題 masked chromosomal abnormality
キーワード
主題Scheme Other
主題 monosomy 7
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Hashimoto, Shigeo

× Hashimoto, Shigeo

WEKO 7242

Hashimoto, Shigeo

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Toba, Ken

× Toba, Ken

WEKO 7243

Toba, Ken

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Izumi, Noriko

× Izumi, Noriko

WEKO 7244

Izumi, Noriko

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Sato, Naoko

× Sato, Naoko

WEKO 7245

Sato, Naoko

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Takahashi, Hidenobu

× Takahashi, Hidenobu

WEKO 7246

Takahashi, Hidenobu

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Ozawa, Takuya

× Ozawa, Takuya

WEKO 7247

Ozawa, Takuya

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Moriyama, Masato

× Moriyama, Masato

WEKO 7248

Moriyama, Masato

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Aoki, Sadao

× Aoki, Sadao

WEKO 7249

Aoki, Sadao

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Furukawa, Tatsuo

× Furukawa, Tatsuo

WEKO 7250

Furukawa, Tatsuo

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Narita, Miwako

× Narita, Miwako

WEKO 7251

Narita, Miwako

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Takahashi, Masuhiro

× Takahashi, Masuhiro

WEKO 7252

Takahashi, Masuhiro

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Aizawa, Yoshifusa

× Aizawa, Yoshifusa

WEKO 7253

Aizawa, Yoshifusa

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著者別名
識別子Scheme WEKO
識別子 7254
姓名 鳥羽, 健
抄録
内容記述タイプ Abstract
内容記述 Therapy related acute myelogenous leukemia in a 55-year-old Japanese woman is described. She had been treated for a diagnosis of non-Hodgkin's lymphoma 2 years before the onset of the secondary leukemia. She was diagnosed as AML (FAB: M2) with monosomy 7, and successfully treated by an intensive combination chemotherapy followed by an autologous peripheral blood stem cell transplantation. The disease relapsed shortly after the treatment, and the karyotype analysis revealed a complex abnormality accompanied with t(9;11)(p22;q23), however, monosomy 7 was absent. Southern blotting analysis was performed, and MLL rearrangement was evident in both the bone marrow samples obtained at that time and the cryopreserved marrow cells obtained at the onset of the disease. The bone marrow sample stored in a Carnoy solution at the onset was further analyzed, and 3 karyotype panels showing 45,XX, -7, t(9;11)(p22;q23) were found. Like this situation, a masked MLL rearrangement may have existed in some cases with hematopoietic malignancies, and appear to be disclosed in the clinical course.
書誌情報 Leukemia Research
en : Leukemia Research

巻 27, 号 3, p. 285-290, 発行日 2003-03
出版者
出版者 Elsevier
ISSN
収録物識別子タイプ ISSN
収録物識別子 01452126
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00716755
DOI
識別子タイプ DOI
関連識別子 info:doi/10.1016/S0145-2126(02)00176-5
権利
権利情報 Elsevier Ltd
著者版フラグ
値 author
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