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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第105巻第9号

5) DIC : この十年間の歩み(新潟血栓止血研究会10周年記念特別例会記録)

http://hdl.handle.net/10191/39392
http://hdl.handle.net/10191/39392
7105f605-fe8c-4f45-b0ce-d98741a32416
名前 / ファイル ライセンス アクション
105(9)_632-638.pdf 105(9)_632-638.pdf (1.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-03-10
タイトル
タイトル 5) DIC : この十年間の歩み(新潟血栓止血研究会10周年記念特別例会記録)
タイトル
言語 en
タイトル 5) DIC : この十年間の歩み(新潟血栓止血研究会10周年記念特別例会記録)
言語
言語 jpn
キーワード
主題Scheme Other
主題 Disseminated intravascular coagulation (DIC)
キーワード
主題Scheme Other
主題 Molecular markers for coagulatin and fibrinolysis
キーワード
主題Scheme Other
主題 Acute promyelocytic leukemia
キーワード
主題Scheme Other
主題 therapy of DIC
キーワード
主題Scheme Other
主題 血管内凝固症候群
キーワード
主題Scheme Other
主題 分子マーカー
キーワード
主題Scheme Other
主題 急性前骨髄球性白血病
キーワード
主題Scheme Other
主題 治療
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Recent Advances in DIC for Ten Years
著者 佐藤, 正之

× 佐藤, 正之

WEKO 130315

佐藤, 正之

Search repository
村川, 英三

× 村川, 英三

WEKO 130316

村川, 英三

Search repository
著者別名
識別子 130317
識別子Scheme WEKO
姓名 Sato, Masayuki
著者別名
識別子 130318
識別子Scheme WEKO
姓名 Murakawa, Eizo
抄録
内容記述タイプ Abstract
内容記述 To diagnose DIC, we have always been looking for new parameters: e.g. fibrinogen and fibrin degradation products (FDP), antithrombinIII (ATIII), α_2 plasmin inhibitor (α_2PI), fibrinmonomer complex (FM) and D dimer (D-D). But these parameters have many problems: FDP can not distinguish between primary fibrinolysis and secondary fibrinolysis. With low plasma levels of ATIII and α_2PI, we can not see they are due to comsumption or due to reduced production. FM is not quantitative analysis. D-D which is specific for secondary fibrinolygis, is too sensitive to assess secondary fibrinolysis in DIC. We evaluated new molecular markers for the diagnosis of DIC in acute promyelocytic leukemia and other disorders: Thrombin antithrombin III complex (TAT) and plasmin・α_2 plasmin inhibitor complex (PIC). TAT and PIC were extremely elevated even though in probable DIC group with DIC scor<4. Abnormal findings of these parameters in probable DIC group seem to show hypercoagulability and fibrinolysis in this group. So plasma levels of TAT and PIC for the diagnosis of DIC should be established. With our data, plasma levels of both TAT≧7.5μg/l and PIC≧2.5μg/ml, three times of normal value, are valuable for the diagnosis of DIC. Recently the therapy of DIC has greatly advanced using synthetic protease inhibitors and ATIII concentrate.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 105, 号 9, p. 632-638, 発行日 1991-09
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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