{"_buckets": {"deposit": "dcaadade-c3c7-46f3-b411-8355b4a631ba"}, "_deposit": {"id": "20737", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20737"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00020737", "sets": ["456", "1169"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Application of Polymerase Chain Reaction (PCR) for the Diagnosis of Infectious Diseases : Rapid diagnosis of Tuberculous Meningitis"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "1013", "bibliographicPageStart": "1008", "bibliographicVolumeNumber": "106", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We have developed a rapid and highly sensitive method for the diagnosis of tuberculous meningitis utilizing polymerase chain reaction (PCR). A crucially important point with this method is how to prevent contaminations without decreasing the sensitivity of PCR. We could successfully avoid DNA contaminations, keeping the high sensitivity as confirmed with the result that we could detect as few as 3 copies of microbial genome DNA. Using this method, we detected the Mycobacterium tuberculosis genome in CSF of 5 of 6 patients with clinically diagnosed tuberculous meningitis. We further applied the method for the analysis of CSF from patients with meningitis of undetermined agents, and detected the Mycobacterium tuberculosis genome in CSF of 2 of 29 patients with clinically suspected tuberculous meningitis. Thus, the method is highly sensitive and rapid to detect the Mycobacterium tuberculosis genome in CSF, and furthermore should be applied for the diagnosis of meningitis caused by various agents.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "127726", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kaneko, Kiyotoshi"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "金子, 清俊"}], "nameIdentifiers": [{"nameIdentifier": "127725", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "106(10)_1008-1013.pdf", "filesize": [{"value": "1.6 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1600000.0, "url": {"label": "106(10)_1008-1013.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/20737/files/106(10)_1008-1013.pdf"}, "version_id": "12e31bc7-d828-4123-9e72-83a2bce0f50e"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "tuberculous meningitis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "rapid diagnosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "polymerase chain reaction (PCR)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "結核性髄膜炎", "subitem_subject_scheme": "Other"}, {"subitem_subject": "迅速診断", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PCR法", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Polymerase Chain Reaction (PCR)法の感染症診断への応用 : 結核性髄膜炎の迅速診断について", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Polymerase Chain Reaction (PCR)法の感染症診断への応用 : 結核性髄膜炎の迅速診断について"}, {"subitem_title": "Polymerase Chain Reaction (PCR)法の感染症診断への応用 : 結核性髄膜炎の迅速診断について", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1169"], "permalink_uri": "http://hdl.handle.net/10191/40060", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-03-25"}, "publish_date": "2016-03-25", "publish_status": "0", "recid": "20737", "relation": {}, "relation_version_is_last": true, "title": ["Polymerase Chain Reaction (PCR)法の感染症診断への応用 : 結核性髄膜炎の迅速診断について"], "weko_shared_id": null}