{"_buckets": {"deposit": "7dc9f34d-28a5-4e31-b64f-7f724674c089"}, "_deposit": {"id": "20026", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20026"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00020026"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Multimodal Treatment of Advanced Neuroblastoma with Intensive Chemotherapy"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1993-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "558", "bibliographicPageStart": "551", "bibliographicVolumeNumber": "107", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Twenty-two pediatric patients with a stage IV-A or IV-B neuroblastoma have been treated with multimodal therapy consisting of intensive chemotherapy and surgery at Niigata University Hospital since 1985. The patients first received six cyclic courses of intensive chemotherapy \uff3bregimen A_1\uff3d, consisting of cyclophosphamide \uff3b1,200mg/m^2\uff3d, vincristine \uff3b1.5mg/m^2], tetrahydropyranyl adriamycin \uff3bpyrarubicin 40mg/m^2\uff3d, and cisplatin \uff3b90mg/m^2\uff3d. Primary tumors and involved regional lymph nodes were removed sometime during first six cycles of chemotherapy. After the six cycles of \uff3bRegiment A_1\uff3d, patients received alternating treatment with \uff3bRegimen A_2\uff3dconsisting of cyclophophamide \uff3b1,500mg/m^2\uff3d, THP-adriamycin \uff3b50mg/m^2\uff3d, cisplatin \uff3b90mg/m^2\uff3d, and \uff3bRegimen C\uff3dconsisting of cyclophosphamide \uff3b1,500mg/m^2\uff3d, DTIC \uff3b250mg/m^2\uff3d. Two-year survival rate was 59%. Nine patients have now survived with disease free at 2 years after initiation of the treatment \uff08survival rate: 41%\uff09. From the viewpoint of prognosis, the influencing factors are as follows: small round cell type, diploidy, VMA\uff08\uff0d\uff09, NSE more than 100ng/ml, N-myc over 8 times of normal value.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "123974", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Iwafuchi, Makoto"}]}, {"nameIdentifiers": [{"nameIdentifier": "123975", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ohsawa, Yoshihiro"}]}, {"nameIdentifiers": [{"nameIdentifier": "123976", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Uchiyama, Masanori"}]}, {"nameIdentifiers": [{"nameIdentifier": "123977", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Matsuda, Yukio"}]}, {"nameIdentifiers": [{"nameIdentifier": "123978", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Naitoh, Shinichi"}]}, {"nameIdentifiers": [{"nameIdentifier": 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