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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

甲状腺手術における近赤外線装置を用いた副甲状腺の同定に関して

http://hdl.handle.net/10191/0002000978
http://hdl.handle.net/10191/0002000978
7d69a8d2-0337-4f5c-b5b3-bbbda81e968c
名前 / ファイル ライセンス アクション
r4nmo1824.pdf 本文 (1.45MB)
r4nmo1824_a.pdf 要旨 (205KB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2023-04-27
タイトル
言語 en
タイトル Near-Infrared Fluorescence Imaging in the Identification of Parathyroid Glands in Thyroidectomy
タイトル
言語 ja
タイトル 甲状腺手術における近赤外線装置を用いた副甲状腺の同定に関して
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Near-infrared fluorescence imaging
キーワード
言語 en
主題Scheme Other
主題 parathyroid gland
キーワード
言語 en
主題Scheme Other
主題 thyroidectomy
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 高橋, 剛史

× 高橋, 剛史

en Takahashi, Takeshi

ja 高橋, 剛史

Search repository
抄録
内容記述タイプ Abstract
内容記述 Objectives/Hypothesis: To assess the ability of near-infrared fluorescence imaging (NIFI) to identify parathyroid glands (PGs) among histologically proven PG/non-PG specimens compared with a surgeon's visual acumen, and to determine NIFI sensitivity in detecting incidentally resected PGs from thyroidectomy specimens, compared to the surgeon's visual inspection. Study Design: Prospective study. Methods: With mean age of 61 years, 36 patients with various thyroid diseases were enrolled. Possible PGs (n=28) and lymph nodes (n=32) were identified by the experienced surgeon's visual inspection. Using NIFI, 15 PGs were further identified from thyroidectomy specimens. For these 75 specimens, the surgeon's judgments (PG vs. non-PG) were recorded. Histological evaluation was performed after examining the NIFI auto-fluorescence of each specimen. Results: There were no significant differences in sensitivity, specificity, positive predictive value, and negative predictive value between the surgeon's visual inspection and NIFI in identifying PGs, with values of 100%/97.1%, 85.0%/87.5%, 85.4%/87.2%, and 100%/97.2%, respectively. The sensitivity of NIFI (82.9%) for detection of PGs from thyroidectomy specimens was significantly higher than that of the surgeon's visual inspection (61.0%). False negative specimens contained bleeding/congestion and/or encapsulation by thick tissues, whereas false positive specimens contained electrocoagulated tissues. Conclusions: NIFI showed results comparable to the experienced surgeon's visual inspection in identifying PGs. This could benefit novice surgeons. NIFI may be useful for experienced surgeons to locate incidentally resected PGs within thyroidectomy specimens for auto-transplantation. Prevention of intra-gland bleeding and congestion, careful removal of thick capsules, and bloodless surgeries without electrocoagulation are important for reducing false positive and false negative results.
言語 en
内容記述
内容記述タイプ Other
内容記述 The Laryngoscope. 2021, 131(5), 1188-1193.
言語 en
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/lary.29163
権利
言語 en
権利情報 © 2021 American Laryngological, Rhinological and Otological Society Inc, "The Triological Society" and American Laryngological Association (ALA)
学位名
言語 ja
学位名 博士(医学)
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 13101
言語 ja
学位授与機関名 新潟大学
言語 en
学位授与機関名 Niigata University
学位授与年月日
学位授与年月日 2022-09-20
学位授与番号
学位授与番号 乙第2266号
学位記番号
内容記述タイプ Other
内容記述 新大博(医)第1824号
言語 ja
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