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網膜前膜における中心窩無血管領域の形態変化と術後視機能との関連
http://hdl.handle.net/10191/0002000310
http://hdl.handle.net/10191/000200031032b56bbb-44dc-46a2-9e62-e3456c032be1
| 名前 / ファイル | ライセンス | アクション |
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本文 (996KB)
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要旨 (545KB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2022-04-04 | |||||||||
| タイトル | ||||||||||
| タイトル | Relationship between morphological changes in the foveal avascular zone of the epiretinal membrane and postoperative visual function | |||||||||
| 言語 | en | |||||||||
| タイトル | ||||||||||
| タイトル | 網膜前膜における中心窩無血管領域の形態変化と術後視機能との関連 | |||||||||
| 言語 | ja | |||||||||
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| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| タイプ | doctoral thesis | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 著者 |
吉田, 博光
× 吉田, 博光
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Objective To investigate the relationship between the preoperative morphology of the foveal avascular zone (FAZ) and postoperative visual function in patients with idiopathic epiretinal membrane (ERM). Methods and analysis This retrospective study enrolled 36 patients who underwent a unilateral internal limiting membrane peeling with vitrectomy for idiopathic ERM. We measured the area of superficial FAZ in the eyes with ERM and in the contralateral control eyes preoperatively and at 6 months postoperatively using optical coherence tomography (OCT) angiography. The ERM stage was measured using swept-source OCT. We evaluated the FAZ area ratio (preoperative FAZ of the ERM eye/FAZ of the control eye) to indicate the degree of FAZ contraction in the ERM eyes compared with the control eyes. The correlations between the FAZ area ratio and postoperative visual function and changes in macular morphology were assessed. Results Preoperative mean best-corrected visual acuity (BCVA) significantly improved from the logarithm of the minimum angle of resolution 0.20±0.24 to 0.01±0.13 at 6 months postoperatively (p<0.01). The mean area of the FAZ increased significantly from 0.06±0.07mm^2 preoperatively to 0.09±0.07mm^2 after vitrectomy (p<0.01). FAZ area ratio showed significant negative correlations with changes in BCVA (r=−0.44, p<0.01) and the ERM stages (r=−0.56, p<0.01). Conclusion The FAZ is reduced as ERM progresses and enlarges after vitrectomy. The FAZ area ratio based on preoperative FAZ may predict postoperative visual acuity. | |||||||||
| 言語 | en | |||||||||
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| 内容記述タイプ | Other | |||||||||
| 内容記述 | BMJ Open Ophthalmology. 5(1), | |||||||||
| 言語 | en | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1136/bmjophth-2020-000636 | |||||||||
| 権利 | ||||||||||
| 言語 | en | |||||||||
| 権利情報 | 【○!C】 Author(s) 2020. | |||||||||
| 権利 | ||||||||||
| 言語 | en | |||||||||
| 権利情報Resource | https://creativecommons.org/licenses/by-nc/4.0/ | |||||||||
| 権利情報 | Creative Commons Attribution-NonCommercial 4.0 International | |||||||||
| 学位名 | ||||||||||
| 言語 | ja | |||||||||
| 学位名 | 博士（医学） | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 13101 | |||||||||
| 言語 | ja | |||||||||
| 学位授与機関名 | 新潟大学 | |||||||||
| 言語 | en | |||||||||
| 学位授与機関名 | Niigata University | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2021-03-23 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第4851号 | |||||||||
| 学位記番号 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 新大院博(医)第1005号 | |||||||||
| 言語 | ja | |||||||||
