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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第108巻第4号

ActivinA/EDF (Erythroid Differentiation Factor) のヒト造血幹細胞分化に及ぼす影響

http://hdl.handle.net/10191/38180
http://hdl.handle.net/10191/38180
ba3a14fe-5fe7-4a00-b9f5-ceb3a9dc7ba8
名前 / ファイル ライセンス アクション
108(4)_301-308.pdf 108(4)_301-308.pdf (1.6 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-10
タイトル
タイトル ActivinA/EDF (Erythroid Differentiation Factor) のヒト造血幹細胞分化に及ぼす影響
タイトル
言語 en
タイトル ActivinA/EDF (Erythroid Differentiation Factor) のヒト造血幹細胞分化に及ぼす影響
言語
言語 jpn
キーワード
主題Scheme Other
主題 EDF (erythroid differentiation factor)
キーワード
主題Scheme Other
主題 erythropoiesis
キーワード
主題Scheme Other
主題 megakaryocytic differentiation
キーワード
主題Scheme Other
主題 cyclo-oxygenase
キーワード
主題Scheme Other
主題 cytokine
キーワード
主題Scheme Other
主題 赤血球分化
キーワード
主題Scheme Other
主題 巨核芽球分化
キーワード
主題Scheme Other
主題 サイクロオキシゲナーゼ
キーワード
主題Scheme Other
主題 造血因子
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Effects of ActivinA/EDF (Erythroid Differentiation Factor) on Differentiation of Human Hematopoietic Stem Cell
著者 後藤, 隆夫

× 後藤, 隆夫

WEKO 120731

後藤, 隆夫

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著者別名
識別子 120732
識別子Scheme WEKO
姓名 Goto, Takao
抄録
内容記述タイプ Abstract
内容記述 ActivinA/EDF (Erythroid Differentiation Factor) purified from the culture fluid of human monocytic cells (THP-1 cells) has shown to be potential to a differentiation murine erythroleukemic cells (Friend cells). In this study, we demonstrated that ActivinA/EDF increases in the number of hemoglobin positive cells in human erythroleukemia cell lines without the reduction of cell proliferation. In addition, it enhances erythroid colony formation from human erythroid progenitors of normal and MDS (myelodysplastic syndrome) in vitro. On the other hand, cyclo-oxygenase (CO) mRNA levels increase in liquid culture of human erythroleukemia cell lines after incubation with ActivinA/EDF by RT-PCR (reverse transcription-polymerase chain reaction). These results suggest that ActivinA/EDF possibly acts as an important cytokine of erythropoiesis and megakaryocytic differentiation of human hematopoietic stem cell.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 108, 号 4, p. 301-308, 発行日 1994-04
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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