{"_buckets": {"deposit": "8daaec72-caf3-44c4-9d93-1ca432c48628"}, "_deposit": {"id": "19243", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "19243"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00019243", "sets": ["456", "1148"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "A Defect in DNA Repair and Neuronal Cell Death Xeroderma Pigmentosum with Neurological Abnormalities"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1994-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "484", "bibliographicPageStart": "481", "bibliographicVolumeNumber": "108", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Xeroderma pigentosum (XP) is a hereditary disease transmitted as an autosomal recessive trait characterized by a high incidence of sunlight-induced skin cancer, and frequent neurological abnormalities. It is well known that cells from XP patients have a defective DNA repair system. We studied neuropathologically two cases of XP with neurological abnormalities (De Sanctis-Cacchione syndrome). The pattern of topographical distribution and severity of neuron loss in the nervous system appeared to be similar to that seen in aged persons or patients with Alzheimer\u0027s disease. However, no senile plaques or neurofibrillary tangles were evident in the present cases. We consider that further studies of this human genetic disease are important for helping to clarify the mechanisms of neuronal cell death in normal cerebral aging as well as in Alzheimer\u0027s disease.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "119875", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Takahashi, Hitoshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "119876", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kakita, Akiyoshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "119877", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ikuta, Fusahiro"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "高橋, 均"}], "nameIdentifiers": [{"nameIdentifier": "119872", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "柿田, 明美"}], "nameIdentifiers": [{"nameIdentifier": "119873", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "生田, 房弘"}], "nameIdentifiers": [{"nameIdentifier": "119874", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-08"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "108(7)_481-484.pdf", "filesize": [{"value": "639.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 639800.0, "url": {"label": "108(7)_481-484.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/19243/files/108(7)_481-484.pdf"}, "version_id": "039f65fb-957e-42f4-b48e-3a60ac397e48"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "xeroderma pigmentosum", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nervous system", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neuron loss", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cerebral aging", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Alzheimer\u0027 s disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "色素性乾皮症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "神経系", "subitem_subject_scheme": "Other"}, {"subitem_subject": "神経細胞脱落", "subitem_subject_scheme": "Other"}, {"subitem_subject": "脳の老化 (加齢)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "アルツハイマー病", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "DNA修復機構の欠陥と神経細胞死 : 神経学的異常を伴う色素性乾皮症", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "DNA修復機構の欠陥と神経細胞死 : 神経学的異常を伴う色素性乾皮症"}, {"subitem_title": "DNA修復機構の欠陥と神経細胞死 : 神経学的異常を伴う色素性乾皮症", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1148"], "permalink_uri": "http://hdl.handle.net/10191/38359", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-02-17"}, "publish_date": "2016-02-17", "publish_status": "0", "recid": "19243", "relation": {}, "relation_version_is_last": true, "title": ["DNA修復機構の欠陥と神経細胞死 : 神経学的異常を伴う色素性乾皮症"], "weko_shared_id": null}