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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第111巻第1号

グリオーマ細胞株におけるがん抑制遺伝子変化の解析

http://hdl.handle.net/10191/44417
http://hdl.handle.net/10191/44417
f7f9ddfb-2bea-435a-94aa-d886e577d914
名前 / ファイル ライセンス アクション
111(1)_47-56.pdf 111(1)_47-56.pdf (1.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-10-21
タイトル
タイトル グリオーマ細胞株におけるがん抑制遺伝子変化の解析
タイトル
言語 en
タイトル グリオーマ細胞株におけるがん抑制遺伝子変化の解析
言語
言語 jpn
キーワード
主題Scheme Other
主題 Glioma
キーワード
主題Scheme Other
主題 Brain tumor
キーワード
主題Scheme Other
主題 Tumor suppressor gene
キーワード
主題Scheme Other
主題 p16 gene
キーワード
主題Scheme Other
主題 p15 gene
キーワード
主題Scheme Other
主題 p53 gene
キーワード
主題Scheme Other
主題 p21 gene
キーワード
主題Scheme Other
主題 グリオーマ
キーワード
主題Scheme Other
主題 脳腫瘍
キーワード
主題Scheme Other
主題 がん抑制遺伝子
キーワード
主題Scheme Other
主題 p16 遺伝子
キーワード
主題Scheme Other
主題 p15 遺伝子
キーワード
主題Scheme Other
主題 p53 遺伝子
キーワード
主題Scheme Other
主題 p21 遺伝子
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Analysis of Tumor Suppressor Gene Alterations in Human Glioma Cell Lines
著者 張, 淑靖

× 張, 淑靖

WEKO 111501

張, 淑靖

Search repository
熊西, 敏郎

× 熊西, 敏郎

WEKO 111502

熊西, 敏郎

Search repository
著者別名
識別子 111503
識別子Scheme WEKO
姓名 Zhang, Shu-Jing
著者別名
識別子 111504
識別子Scheme WEKO
姓名 Kumanishi, Toshiro
抄録
内容記述タイプ Abstract
内容記述 Ten glioma cell lines were examined for alterations of the p16, p15 and p53 genes, which were tumor suppressor genes with direct or indirect CDK inhibitory functions. All the cell lines showed abnormalities in at least 1 gene, often in 2 or 3 genes coincidentally, suggesting that dysfunction of these genes is closely related to glioma cell growth. On examination of the primary tumor tissues, the same alterations of the p16/p15 and p53 genes as detected in the cell lines were demonstrated in all 6 cases examined, p16/p15 gene deletion in 1, p16 gene mutation in 1 and p53 gene mutations in 5 cases. This suggested that the p16/p15 and p53 gene alterations and their combinations in at least some glioma cell lines reflected those in the primary glioma tissues.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 111, 号 1, p. 47-56, 発行日 1997-01
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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