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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第111巻第8号

Modified Blalock-Taussig手術における短絡流量の段階的増加法に関する実験的研究

http://hdl.handle.net/10191/45212
http://hdl.handle.net/10191/45212
775c75c3-ffca-4f96-a2e4-59dce656046a
名前 / ファイル ライセンス アクション
111(8)_496-508.pdf 111(8)_496-508.pdf (4.7 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-12-22
タイトル
タイトル Modified Blalock-Taussig手術における短絡流量の段階的増加法に関する実験的研究
タイトル
言語 en
タイトル Modified Blalock-Taussig手術における短絡流量の段階的増加法に関する実験的研究
言語
言語 jpn
キーワード
主題Scheme Other
主題 modified Blalock-Taussig operation
キーワード
主題Scheme Other
主題 excessive shunt flow
キーワード
主題Scheme Other
主題 polydioxanone absorbable clip
キーワード
主題Scheme Other
主題 balloon angioplasty
キーワード
主題Scheme Other
主題 Blalock-Taussig 手術変法
キーワード
主題Scheme Other
主題 過剰短絡流量
キーワード
主題Scheme Other
主題 ポリディオキサノン吸収性クリップ
キーワード
主題Scheme Other
主題 バルーン血管形成術
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Experimental Study of Staged Increase in Shunt Flow for Modified Blalock-Taussig Operation
著者 名村, 理

× 名村, 理

WEKO 108786

名村, 理

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著者別名
識別子 108787
識別子Scheme WEKO
姓名 Namura, Osamu
抄録
内容記述タイプ Abstract
内容記述 Currently, a modified Blalock-Taussig procedure with an expanded polytetrafluoroethylene (ePTFE) tube is generally used in children with cyanotic heart disease. Congestive heart failure due to excessive shunt flow is one of the complications of this procedure. We experimented with a new technique in which the ePTFE was stenosed by an absorbable material and the shunt flow was decreased to prevent excessive flow in the acute postoperative stage. Left modified Blalock-Taussig shunts using 5mm thin-walled ePTFE tubes were created in 9 beagle dogs. In group A (n=3) and group B (n=3), the shunts were pinched by polydioxanone absorbable clips and the shunt flow was decreased. In group C (n=3), the shunt was not pinched. At 4 weeks after the operation, in group A, the pinched site was dilated by means of balloon angioplasty. At 4 weeks after the operation, the dogs in group B were sacrificed and the grafts were removed. In groups A and C, at 12 weeks after the operation, the dogs were sacrificed and the grafts were removed. In group A, when the shunts were pinched by clips, a rate of decrease in the shunt flow were 80.0, 66.8 and 78.4%, respectively. Balloon angioplasty dilated the pinched sites completely and a rate of increase in the shunt flow were 54.1, 33.2 and 30.7%, respectively. In group A, light microscopic examination of the grafts showed that the lumens wete covered with a pseudointima organized by fibrin and cellulofibrous tissues. In group B, these sites were covered with a fibrin layer with leukocytes at the pinched sites. In group C, the lumens were covered with a pseudointima organized by cellulofibrous tissues in the middle of each graft. The extent of pseudointimal thickening was greater in groups A and B than in group C. In conclusion, a staged increase in shunt flow is feasible using this technique and prevents excessive shunt flow after modified Blalock-Taussig operation. However, further investigation is needed to prevent pseudointimal hyperplasia and a delay in healing mechanism of ePTFE tube.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 111, 号 8, p. 496-508, 発行日 1997-08
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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