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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第111巻第12号

ブタ前脊髄動脈に及ぼす局所麻酔薬及びエピネフリンの直接作用

http://hdl.handle.net/10191/45635
http://hdl.handle.net/10191/45635
179cd195-6102-4e5e-b2ee-ec6961f81f48
名前 / ファイル ライセンス アクション
111(12)_757-766.pdf 111(12)_757-766.pdf (1.8 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-01-18
タイトル
タイトル ブタ前脊髄動脈に及ぼす局所麻酔薬及びエピネフリンの直接作用
タイトル
言語 en
タイトル ブタ前脊髄動脈に及ぼす局所麻酔薬及びエピネフリンの直接作用
言語
言語 jpn
キーワード
主題Scheme Other
主題 local anesthetics
キーワード
主題Scheme Other
主題 anterior spinal artery
キーワード
主題Scheme Other
主題 membrane potential
キーワード
主題Scheme Other
主題 micro-circulation analyzing system
キーワード
主題Scheme Other
主題 局所麻酔薬
キーワード
主題Scheme Other
主題 前脊髄動脈
キーワード
主題Scheme Other
主題 膜電位
キーワード
主題Scheme Other
主題 微小循環解析装置
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Effects of Local Anesthetics and Epinephrine on Porcine Anterior Spinal Artery in Vitro
著者 黒川, 智

× 黒川, 智

WEKO 107114

黒川, 智

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著者別名
識別子 107115
識別子Scheme WEKO
姓名 Kurokawa, Satoshi
抄録
内容記述タイプ Abstract
内容記述 Effects of lidocaine, mepivacaine, bupivacaine and epinephrine on intraluminal diameter of the pressurized porcine anterior spinal artery were studied using a micro-circulation analyzing system with a video dimension analyzer. Lidocaine, 10^<-3> to 10^<-2>M, induced vasodilation in a dose-dependent manner. By contrast, low concentration of mepivacaine and bupivacaine constricted the arteries, whereas high concentrations dilated them. Epinephrine dose-dependently dilated the artery. When 10^<-5>M epinephrine was added to lidocaine, the artery was dilated. The membrane potential was depolarized by 10^<-2>M lidocaine and 3×10^<-3> to 10^<-2>M mepivacaine. The present study indicates that choice of local anesthetics for spinal anesthesia is important for evaluating the spinal circulation since the action of local anesthetics on the spinal artery differs. Another important finding of this study is the constricting effects of low concentration of mepivacaine and bupivacaine, suggesting that spinal cord ischemia may occur when using these local anesthetics. It appears that addition of epinephrine to local anesthetics may prevent spinal vasoconstriction caused by these local anesthetics.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 111, 号 12, p. 757-766, 発行日 1997-12
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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