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心室頻拍の電気生理学的基盤と治療の進展
http://hdl.handle.net/10191/45911
http://hdl.handle.net/10191/4591176cdfc34-6150-4617-a7db-72a79fd81acb
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
112(6)_295-304.pdf (1.8 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-02-01 | |||||
| タイトル | ||||||
| タイトル | 心室頻拍の電気生理学的基盤と治療の進展 | |||||
| タイトル | ||||||
| タイトル | 心室頻拍の電気生理学的基盤と治療の進展 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | sustained ventricular tachycardia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | electrophysiologic study | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | reentry | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | excitable gap | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | electrropharmacology | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | central common pathway | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 持続性心室頻拍 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | リエントリー | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 興奮間隙 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 電気生理・薬理学的検査 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 緩徐伝導路 | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Electrophysiology of Sustained Ventricular Tachycardia | |||||
| 著者 |
相澤, 義房
× 相澤, 義房 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 105901 | |||||
| 姓名 | Aizawa, Yoshifusa | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Monomorpic sustained ventricular tachycardia (MSVT) was revisited in relation to the electrophysiologic findings and its application in understanding the mechanism of MSVT and the drug-efficacy. As the underlying heart disease, old myocardial infarction is less common cause of MSVT in Japan (< 1/3), and the majority of MSVT is unrelated to coronary artery disease. However, the mechanism shared a common mechanism：reentry with an excitable gap, as others. The reentrant mechanism has been supported from several electrophysiological findings. Of these, the ability to entrain VT with rapid pacing would be most strong evidence for reentrant mechanism and this could be shown in non-ischemic MSVT. However, the conductive property of the reentrant circuit has been shown to be non-uniform； varying from a case to another and their clinical implications were suggested from our studies. In MSVT associated with underlying heart disease, diseased myocardium showed low amplitude and fragmented electrograms and the area was considered to participate as the central common pathway of reentrant circuit and a preferential action of antiarrhythmic drug on it was shown in all VT studied. As to the drug efficacy, there was no baseline characteristics in predicting the efficacy. However, the significant narrowing of the width of the excitable gap was associated with the drug efficacy and VT became non-inducible after addition of the same drug. The response pattern of the excitable gap to specific drug including class III, was not predictable and further electropharmacological studies will be warranted. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 112, 号 6, p. 295-304, 発行日 1998-06 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
