{"_buckets": {"deposit": "7c752ae6-0772-41b1-9cef-d681c64f45a9"}, "_deposit": {"id": "1651", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "1651"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00001651", "sets": ["454", "487"]}, "item_5_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "198", "bibliographicPageStart": "193", "bibliographicVolumeNumber": "58", "bibliographic_titles": [{"bibliographic_title": "Experimental animals"}, {"bibliographic_title": "Experimental animals", "bibliographic_titleLang": "en"}]}]}, "item_5_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Genetic bases of glomerulonephritis, a major cause of kidney dysfunction in humans and one of the most characteristic complications of autoimmune disorders such as Goodpasture syndrome, are complex. The Wistar-Kyoto (WKY) rat strain is well characterized for its susceptibility to autoantibodies against glomerular basement membrane (GBM), however the molecular mechanisms underlining the phenotype are largely unknown. Here we performed a whole genome scan using a backcross (BC) F1 (WKY × DA) × WKY population, for which the DA rat is a nonsusceptible control strain. We found two significant QTLs on chromosomes 1 and 12, which were involved in elevated levels of proteinuria and kidney weight index, respectively. The relevance of these QTLs with the genetic factors involved in autoimmunity and renal disease is discussed.", "subitem_description_type": "Abstract"}]}, "item_5_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Japanese Association for Laboratory Animal Science"}]}, "item_5_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.1538/expanim.58.193", "subitem_relation_type_select": "DOI"}}]}, "item_5_relation_31": {"attribute_name": "異版である", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.jstage.jst.go.jp/article/expanim/58/2/58_2_193/_pdf", "subitem_relation_type_select": "URI"}}]}, "item_5_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright(C)2009 Japanese Association for Laboratory Animal Science"}, {"subitem_rights": "本文データは学協会の許諾に基づきJ-Stageから複製したものである"}]}, "item_5_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_5_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11032321", "subitem_source_identifier_type": "NCID"}]}, "item_5_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "13411357", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kose, Hiroyuki"}], "nameIdentifiers": [{"nameIdentifier": "4800", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sado, Yoshikazu"}], "nameIdentifiers": [{"nameIdentifier": "4801", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamada, Takahisa"}], "nameIdentifiers": [{"nameIdentifier": "4802", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Kozo"}], "nameIdentifiers": [{"nameIdentifier": "4803", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-07-29"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "58_2_193-198.pdf", "filesize": [{"value": "524.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 524300.0, "url": {"label": "58_2_193-198.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/1651/files/58_2_193-198.pdf"}, "version_id": "dc19cee7-ce11-4864-a953-9eac4e644186"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "glomerulonephritis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "QTL", "subitem_subject_scheme": "Other"}, {"subitem_subject": "analysis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "WKY rat", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Genetic Mapping Found Major QTLs for Antibody-Induced Glomerulonephritis in WKY Rats", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Genetic Mapping Found Major QTLs for Antibody-Induced Glomerulonephritis in WKY Rats"}, {"subitem_title": "Genetic Mapping Found Major QTLs for Antibody-Induced Glomerulonephritis in WKY Rats", "subitem_title_language": "en"}]}, "item_type_id": "5", "owner": "1", "path": ["454", "487"], "permalink_uri": "http://hdl.handle.net/10191/30608", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-12-01"}, "publish_date": "2014-12-01", "publish_status": "0", "recid": "1651", "relation": {}, "relation_version_is_last": true, "title": ["Genetic Mapping Found Major QTLs for Antibody-Induced Glomerulonephritis in WKY Rats"], "weko_shared_id": null}