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アイテム
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透析アミロイドーシスの臨床・病理学的特徴
http://hdl.handle.net/10191/46031
http://hdl.handle.net/10191/460314a772f7b-340e-4ea2-aeac-aa0b8afd5f65
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-02-03 | |||||
タイトル | ||||||
タイトル | 透析アミロイドーシスの臨床・病理学的特徴 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 透析アミロイドーシスの臨床・病理学的特徴 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hemodialysis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | amyloidosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β2-microglobulin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | glycoprotein | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | advanced glycation endproduct | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | macrophage | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 血液透析 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β2ミクログロブリン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 糖蛋白 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 非酵素的糖化終末産物 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | マクロファージ | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Clinical and Pathological Features of Hemodialysis Associated Amyloidosis | |||||
著者 |
西, 慎一
× 西, 慎一 |
|||||
著者別名 | ||||||
識別子 | 104962 | |||||
識別子Scheme | WEKO | |||||
姓名 | Nishi, Shinichi | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Hemodialysis associated amyloidosis (HA) is a new type systemic amyloidosis. Gejyo elucidated precursor protein of HA was β2-microglobulin (β2-MG), which was a low molecular protein accumulating in the serum of long term hemodialysis patients, in 1985. The histological features of this amyloidosis, which are unique in fiblilar structures and histochemical characters, are clearly different from those of other types of systemic amyloidosis, AL and AA. HA shows specific aspects in clinical features, either. The incidence of various bone and articular complications, such as bone cysts, carpal tunnel syndrome and destructive spondylarthropathy, increases according to the duration of hemodialysis. These complications result from the deposition of amyloid fibrils derived from β2-MG and are suspected to be confirmed in all patients who continue the dialysis treatment more than 10 years. The affinity of amyloid deposition to bone and articular tissues supposed to be an interesting key character in the pathogenic consideration of amyloid fibril formation. We discussed clinical and histological features of HA and summarized the recent studies of pathogenesis about amyloidgenesis including in our research results. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 112, 号 8, p. 443-448, 発行日 1998-08 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |