WEKO3
アイテム
Pulpal responses to cavity preparation in aged rat molars
http://hdl.handle.net/10191/1803
http://hdl.handle.net/10191/1803cee22ba5-8bc0-4f00-a54d-92fcbaefafa8
名前 / ファイル | ライセンス | アクション |
---|---|---|
9_0005.pdf (114.2 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-05-10 | |||||
タイトル | ||||||
タイトル | Pulpal responses to cavity preparation in aged rat molars | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dental cavity preparation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | heat-shock proteins | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | histocompatibility antigens class II | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | odontoblasts | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rats (Wistar) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kawagishi, Eriko
× Kawagishi, Eriko× Nakakura-Ohshima, Kuniko× Nomura, Shuichi× Ohshima, Hayato |
|||||
著者別名 | ||||||
識別子Scheme | WEKO | |||||
識別子 | 14 | |||||
姓名 | 大島, 勇人 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The dentin-pulp complex is capable of repair after tooth injuries including dental procedures. However, there are few available data concerning aged changes in pulpal reactions to such injuries. The present study aimed to clarify the capability of defense of aged pulp by investigating the responses of odontoblasts and class II major histocompatibility complex (MHC)-positive cells to cavity preparation in aged rat molars (300-360 d) and comparing the results with those in young adult rats (100 d). In untreated control teeth, intense heat-shock protein (HSP)-25- and nestin-immunoreactivity (IR) was found in the odontoblasts, whereas class II MHC-positive cells were densely distributed in the periphery of the pulp. Cavity preparation caused the two types of pulpal reactions showing the different extent of damage in the aged rats. In the case of severe damage, the destruction of the odontoblast layer was conspicuous at the affected site. Twelve h after cavity preparation, numerous class II MHC-positive cells appeared along the pulp-dentin border, but subsequently disappeared together with HSP-25-immunopositive cells, and finally newly differentiated odontoblast-like cells took the place of the degenerated odontoblasts and acquired HSP-25- and nestin-IR by postoperative 3 d. In the case of mild damage, there seemed no remarkable changes in the odontoblasts after operation, and some could survive through the experimental stages. These findings indicate that aged pulp tissue still possesses the defense capacity, and that a variety of reactions could occur depending on the difference in the status of dentinal tubules and/or odontoblast processes in individuals. | |||||
書誌情報 |
Cell and tissue research en : Cell and tissue research 巻 326, 号 1, p. 111-122, 発行日 2006-10 |
|||||
出版者 | ||||||
出版者 | Springer Berlin/Heidelberg | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0302766X | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00600105 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1007/s00441-006-0230-4 | |||||
権利 | ||||||
権利情報 | Springer-Verlag 2006 | |||||
著者版フラグ | ||||||
値 | author |