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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第114巻第5号

医療統計学を用いた新しい治療効果判定法の開発

http://hdl.handle.net/10191/48941
http://hdl.handle.net/10191/48941
3bdcf71c-fa1c-4490-b4e5-b819e738e76e
名前 / ファイル ライセンス アクション
114(5)_179-185.pdf 114(5)_179-185.pdf (1.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-11-20
タイトル
タイトル 医療統計学を用いた新しい治療効果判定法の開発
タイトル
言語 en
タイトル 医療統計学を用いた新しい治療効果判定法の開発
言語
言語 jpn
キーワード
主題Scheme Other
主題 randomized clinical trial
キーワード
主題Scheme Other
主題 sruvival time
キーワード
主題Scheme Other
主題 treatment effect
キーワード
主題Scheme Other
主題 Cox regression method
キーワード
主題Scheme Other
主題 piecewise linear hazard model
キーワード
主題Scheme Other
主題 無作為化臨床試験
キーワード
主題Scheme Other
主題 生存時間
キーワード
主題Scheme Other
主題 治療効果
キーワード
主題Scheme Other
主題 Cox回帰法
キーワード
主題Scheme Other
主題 折れ線ハザードモデル
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル An Alternative Statistical Method to Evaluate the Treatment Effect in Randomized Clinical Trials
著者 赤澤, 宏平

× 赤澤, 宏平

WEKO 99085

赤澤, 宏平

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著者別名
識別子 99086
識別子Scheme WEKO
姓名 Akazawa, Kohei
抄録
内容記述タイプ Abstract
内容記述 This paper evaluates the loss of power of the simple and stratified logrank tests due to heterogeneity of patients in clinical trials. The results of the paper are based on the analyses of survival data from a large clinical trial which includes more than 6,000 cancer patients. Major findings from the simulation study on power are : (1) for a heterogeneous sample, such as advanced cancer patients, a simple logrank test can yield misleading results and should not be used;(2)the stratified logrank test may suffer some power loss when many prognostic factors need to be considered and the number of patients within stratum is small. To address the problems, due to heterogeneity, the Cox regression method with a piecewise linear hazard model is recommended.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 114, 号 5, p. 179-185, 発行日 2000-05
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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